Information processing efficiency in patients with multiple sclerosis.

Information processing efficiency in patients with multiple sclerosis. Research Abstract Details 

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Information processing efficiency in patients with multiple sclerosis. Abstract Text:

Reduced information processing efficiency, consequent to impaired neural transmission, has been proposed as underlying various cognitive problems in patients with Multiple Sclerosis (MS). This study employed two measures developed from experimental psychology that control for the potential confound of perceptual-motor abnormalities (Salthouse, Babcock, & Shaw, 1991; Sternberg, 1966, 1969) to assess the speed of information processing and working memory capacity in patients with mild to moderate MS. Although patients had significantly more cognitive complaints than neurologically intact matched controls, their performance on standard tests of immediate memory span did not differ from control participants and their word list learning was within normal limits. On the experimental measures, both relapsing-remitting and secondary-progressive patients exhibited significantly slowed information processing speed relative to controls. However, only the secondary-progressive patients had an additional decrement in working memory capacity. Depression, fatigue, or neurologic disability did not account for performance differences on these measures. While speed of information processing may be slowed early in the disease process, deficits in working memory capacity may appear only as there is progression of MS. It is these latter deficits, however, that may underlie the impairment of new learning that patients with MS demonstrate.

Information processing efficiency in patients with multiple sclerosis. Publishing Authors By Initials

For similar psychological phenomena and processes: mental processes: learning: verbal learning research abstracts see: psychological phenomena and processes: mental processes: learning: verbal learning research

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Information processing efficiency in patients with multiple sclerosis. Journal Published:

PUBLICATION TYPE: Research Support, Non-U.S. Gov

Journal: Journal of clinical and experimental neuropsycholo

VOLUME: 22

Page Numbers: 686-701

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ISSN: 1380-3395

DAY: 14

MONTH: Oct

YEAR: 2000

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LANGUAGE: eng

NlmUniqueID: 8502170

Information processing efficiency in patients with multiple sclerosis. Keywords Mesh Terms:

KEYWORDS: Verbal Learning

MESH TERMS: psychology

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AFFILIATION: archibc.cadvision.com

Country: NETHERLANDS

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MEDLINETA: J Clin Exp Neuropsychol

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