Information given to postmenopausal women on coronary computed tomography may influence cardiac risk reduction efforts.

Information given to postmenopausal women on coronary computed tomography may influence cardiac risk reduction efforts. Research Abstract Details 

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Information given to postmenopausal women on coronary computed tomography may influence cardiac risk reduction efforts. Abstract Text:

Jeffrey Lederman,Jennifer Ballard,Valentine Y Njike,Laurie Margolies,David L Katz,

OBJECTIVE: Cardiovascular disease (CVD) is largely preventable through appropriate risk-factor modification. We sought to compare effects of comprehensive cardiac risk factor screening with and without computed tomography (CT) imaging of the coronary arteries on behavior change related to cardiac risk in postmenopausal women. STUDY DESIGN AND SETTING: 56 postmenopausal women were randomized to alternative screening programs and followed for 1 year. RESULTS: Subjects randomized (n=26) to the CT imaging group were shown images of their coronary arteries and received an interpretation from a radiologist. Most subjects in the CT group had a very low-risk (73.1%) coronary calcification score at baseline. Systolic blood pressure, total cholesterol, triglyceride, LDL, and cholesterol/HDL ratio declined significantly in the conventional screening group, but not in the CT imaging group (P<0.05). As compared to baseline values, study participation lead to significant reductions in total cholesterol, HDL, LDL, and blood pressure at 6 months (P<0.05) and triglyceride (P<0.05) at 12 months. CONCLUSIONS: CVD risk-screening programs can facilitate cardiac risk reduction in women, but these data do not support an independent benefit of coronary CT imaging in a low-to-moderate risk group. The possibility of a deleterious effect of imaging on patient commitment to lifestyle changes is suggested.

Information given to postmenopausal women on coronary computed tomography may influence cardiac risk reduction efforts. Publishing Authors By Initials

J Lederman,J Ballard,VY Njike,L Margolies,DL Katz,

For similar tomography, x-ray computed research abstracts see: tomography, x-ray computed research

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Information given to postmenopausal women on coronary computed tomography may influence cardiac risk reduction efforts. Journal Published:

PUBLICATION TYPE: Research Support, U.S. Gov't,

Journal: Journal of clinical epidemiology

VOLUME: 60

Page Numbers: 389-96

Journal Abbreviation:

ISSN: 0895-4356

DAY: 11

MONTH: 12

YEAR: 2006

Information given to postmenopausal women on coronary computed tomography may influence cardiac risk reduction efforts. Information

Number of References:

LANGUAGE: eng

NlmUniqueID: 8801383

Information given to postmenopausal women on coronary computed tomography may influence cardiac risk reduction efforts. Keywords Mesh Terms:

KEYWORDS: Tomography, X-Ray Computed

MESH TERMS: methods

Chemical & Substance for Abstract: Information given to postmenopausal women on coronary computed tomography may influence cardiac risk reduction efforts. Information

Substance Name: Cholesterol

Registry Number: 57-88-5

Grant and Affiliation Information for Information given to postmenopausal women on coronary computed tomography may influence cardiac risk reduction efforts.

AFFILIATION: Yale Prevention Research Center, 130 Division Street, Derby, CT 06418, USA.

Country: England

AGENCY: United States PHS

GRANT: U48/CCU115802

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MEDLINETA: J Clin Epidemiol

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