Influence of probiotic Lactobacilli colonization on neonatal B cell responses in a gnotobiotic pig model of human rotavirus infection and disease.

Influence of probiotic Lactobacilli colonization on neonatal B cell responses in a gnotobiotic pig model of human rotavirus infection and disease. Research Abstract Details 

Research Abstract Table of Contents

Jump to the:

Influence of probiotic Lactobacilli colonization on neonatal B cell responses in a gnotobiotic pig model of human rotavirus infection and disease. Abstract Text:

Wei Zhang,Marli S P Azevedo,Ana M Gonzalez,Linda J Saif,Trang Van Nguyen,Ke Wen,Ahmed E Yousef,Lijuan Yuan,

The goal of this study was to define the impact of colonization of gnotobiotic (Gn) pigs with lactic acid bacteria (LAB) on development of intestinal and systemic B cell responses to human rotavirus (HRV). The LAB-specific and total B cell responses were also assessed. Gn pigs were inoculated with LAB (Lactobacillus acidophilus and L. reuteri) and virulent Wa strain HRV (LAB+HRV+), HRV only (LAB-HRV+), LAB only (LAB+HRV-) or mock (LAB-HRV-). The HRV infection induced similar HRV-specific intestinal and systemic antibody and B cell responses in pigs with or without LAB, whereas LAB significantly enhanced total intestinal IgA secreting cell responses and total serum IgM and intestinal IgM and IgG titers. The LAB colonization did not reduce HRV shedding or diarrhea, this may be partly due to the short time interval between the first LAB feeding and HRV inoculation. Further studies are needed with longer time for LAB to establish before HRV inoculation. However, our studies demonstrate that Gn pigs infected with HRV develop a similar magnitude of virus-specific B cell responses as those of HRV-infected and LAB colonized pigs. LAB colonization alone is not as efficient in promoting intestinal B cell responses, as is HRV infection.

Influence of probiotic Lactobacilli colonization on neonatal B cell responses in a gnotobiotic pig model of human rotavirus infection and disease. Publishing Authors By Initials

W Zhang,MS Azevedo,AM Gonzalez,LJ Saif,T Van Nguyen,K Wen,AE Yousef,L Yuan,

For similar abstracts research abstracts see: abstracts research

PUBMED ID PMID:

MEDLINE DATE:

Influence of probiotic Lactobacilli colonization on neonatal B cell responses in a gnotobiotic pig model of human rotavirus infection and disease. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Veterinary immunology and immunopathology

VOLUME: 122

Page Numbers: 175-81

Journal Abbreviation: Vet. Immunol. Immunopathol.

ISSN: 0165-2427

DAY: 10

MONTH: 10

YEAR: 2007

Influence of probiotic Lactobacilli colonization on neonatal B cell responses in a gnotobiotic pig model of human rotavirus infection and disease. Information

Number of References:

LANGUAGE: eng

NlmUniqueID: 8002006

Influence of probiotic Lactobacilli colonization on neonatal B cell responses in a gnotobiotic pig model of human rotavirus infection and disease. Keywords Mesh Terms:

KEYWORDS:

MESH TERMS:

Chemical & Substance for Abstract: Influence of probiotic Lactobacilli colonization on neonatal B cell responses in a gnotobiotic pig model of human rotavirus infection and disease. Information

Substance Name:

Registry Number:

Grant and Affiliation Information for Influence of probiotic Lactobacilli colonization on neonatal B cell responses in a gnotobiotic pig model of human rotavirus infection and disease.

AFFILIATION: Food Animal Health Research Program, Department of Veterinary Preventive Medicine, Ohio Agricultural Research and Development Center, The Ohio State University, 1680 Madison Avenue, Wooster, OH 44691-4096, USA.

Country: Netherlands

AGENCY:

GRANT:

ACRONYM:

MEDLINETA: Vet Immunol Immunopathol

REFSOURCE:

DATABASENAME:

ACCESSION NUMBER:

Number Hits: 0

Influence of probiotic Lactobacilli colonization on neonatal B cell responses in a gnotobiotic pig model of human rotavirus infection and disease Related Publications

• A remote controlled multimode micro-stimulator for freely moving animals.
• Bone morphogenetic proteins induce apoptosis in human pulmonary vascular smooth muscle cells.
• Experimental study on effects of vitamin B(6) on dexamethason-induced palatal cleft formation in the rat.
• Pentacyclic Triterpenoids from Leaves of Excoecaria agallocha.
• Steroid withdrawal in the mouse results in anxiogenic effects of 3alpha,5beta-THP: a possible model of premenstrual dysphoric disorder.
• [Changes in the phosphorylation of cAMP response element binding protein in the rat nucleus accumbens after acute and chronic ethanol administration]
• [Clinical features in 4 Chinese families with cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL).]
• [Clinical pathology and molecular genetics on familial amyloidotic polyneuropathy]
• [Clinical study on improving the diagnostic criteria for neonatal asphyxia]
• [Comparing loss of anterior column height and cervical Cobb angle with three different types of anterior cervical discectomy and fusion]
• [Detection of desmosine in elastin by high performance liquid chromatography (HPLC)]
• [Development of a portable glucose meter based on PIC microcomputer]
• [Effects of platelet-rich plasma on proliferation and osteogenetic activity of marrow mesenchymal stem cells in vitro]
• [Effects of urotensin II on isolated rat hearts under normal perfusion and ischemia reperfusion]
• [Expression of midkine in eutopic and ectopic endometrium of patients with severe endometriosis and its clinical significance]
• [Fermentation process monitoring and fault detection based on dynamic MPCA]
• [Isolation of endophytic bacteria in potato and test of antagonistic action to bacterial ring rot of potato]
• [Measuring trace germanium in vegetables with the spectrofluorometric method]
• [Pelvic artery representation on three-dimensional reconstructed multislice spiral CT images: variability between the young and the elderly]
• [Photoluminescence and UV-Vis absorption spectra characteristics of metal complexes of 8-hydroxyquinoline]
• [Properties and advance of hepcidin]
• [Research and advancement of image-guided radiotherapy]
• [Significance of serum level of NO and IL-8 in helicobacter pylori associated gastric diseases]
• [Space flight and peroxidative damage]
• [Spectral properties of broad emission bands of Cr3+ in A3M2Ge3O12 (A = Cd2+, Ca2+; M = AI3+, Ga3+, Sc3+) garnets]
• [Spectral study of the conformational change of yeast alcohol dehydrogenase induced by alcohol]
• [Study of the volatilization inhibitor for formalin]
• [Synthesis and spectral properties of tailed sercine tetraphenylporphyrin cobalt complex]
• [The antimicrobial effects of chitosans on oral pathogenic microbes in vitro]
• [The evolvement of the theory of dental implant-bone interface]