Influence of crystalloid and colloid replacement solutions on hemodynamic variables during acute normovolemic hemodilution.

Influence of crystalloid and colloid replacement solutions on hemodynamic variables during acute normovolemic hemodilution. Research Abstract Details 

Research Abstract Table of Contents

Jump to the:

Influence of crystalloid and colloid replacement solutions on hemodynamic variables during acute normovolemic hemodilution. Abstract Text:

STUDY OBJECTIVE: To determine whether, in maintaining normovolemia during acute normovolemic hemodilution, replacement fluid choice influences intraoperative hemodynamic variables. DESIGN: Prospective, randomized, single-blinded study. SETTING: Operating room of a tertiary-care university hospital. PATIENTS: 40 adult, ASA physical status I, II, and III patients scheduled for acute normovolemic hemodilution during radical prostatectomy. INTERVENTIONS: Patients were randomly assigned to four replacement fluid groups to receive 1) Ringer's lactate, 2) 5% albumin, 3) 6% dextran 70, or 4) 6% hetastarch. A standardized general anesthetic was used, and patients underwent moderate hemodilution to a target hemoglobin of 9 gm/dL. MEASUREMENTS: Hemodynamic variables were recorded using standard monitors, 5-lead electrocardiography, radial arterial catheter, and pulmonary artery catheter. Red blood cell loss for the entire hospitalization was calculated. MAIN RESULTS: Demographic and clinical outcome data were similar among the groups. During acute normovolemic hemodilution, heart rate and pulmonary capillary wedge pressure were unchanged from baseline in all groups, but patients receiving Ringer's lactate or albumin had greater declines in mean arterial pressure at the end of acute normovolemic hemodilution. Cardiac and oxygen consumption indexes were stable during acute normovolemic hemodilution, but oxygen extraction increased. CONCLUSIONS: During hemodilution, anesthetized patients maintain whole body oxygenation by increasing oxygen extraction. The administration of hetastarch or dextran as the replacement fluid during acute normovolemic hemodilution is associated with a more stable mean arterial pressure, but overall acute normovolemic hemodilution is well tolerated irrespective of the replacement fluid used.

Influence of crystalloid and colloid replacement solutions on hemodynamic variables during acute normovolemic hemodilution. Publishing Authors By Initials

For similar abstracts research abstracts see: abstracts research

PUBMED ID PMID:

MEDLINE DATE:

Influence of crystalloid and colloid replacement solutions on hemodynamic variables during acute normovolemic hemodilution. Journal Published:

PUBLICATION TYPE: Randomized Controlled Trial

Journal: Journal of clinical anesthesia

VOLUME: 16

Page Numbers: 11-7

Journal Abbreviation:

ISSN: 0952-8180

DAY: 4

MONTH: Feb

YEAR: 2004

Influence of crystalloid and colloid replacement solutions on hemodynamic variables during acute normovolemic hemodilution. Information

Number of References:

LANGUAGE: eng

NlmUniqueID: 8812166

Influence of crystalloid and colloid replacement solutions on hemodynamic variables during acute normovolemic hemodilution. Keywords Mesh Terms:

KEYWORDS: Single-Blind Method

MESH TERMS: pharmacology

Chemical & Substance for Abstract: Influence of crystalloid and colloid replacement solutions on hemodynamic variables during acute normovolemic hemodilution. Information

Substance Name: Hetastarch

Registry Number: 9005-27-0

Grant and Affiliation Information for Influence of crystalloid and colloid replacement solutions on hemodynamic variables during acute normovolemic hemodilution.

AFFILIATION: Department of Anesthesiology, Washington University School of Medicine, St. Louis, MO, USA. sbjones@bidm.harvard.edu

Country: United States

AGENCY:

GRANT:

ACRONYM:

MEDLINETA: J Clin Anesth

REFSOURCE: J Clin Anesth. 2008 Jun;20(4):324

DATABASENAME:

ACCESSION NUMBER:

Number Hits: 0

Influence of crystalloid and colloid replacement solutions on hemodynamic variables during acute normovolemic hemodilution Related Publications

• A Visual Analogue Scale technique to measure global vigor and affect.
• A curious eruption: erythema gyratum repens in resolving pustular psoriasis.
• Age wise: aging well by sleeping well.
• An efficient screening tool for preoperative depression: the geriatric depression scale-short form.
• Candida albicans drug resistance another way to cope with stress.
• Cervical neoplasia in pregnancy. Part 2: current treatment of invasive disease.
• Comparative agonist/antagonist responses in mutant human C5a receptors define the ligand binding site.
• Conference report for the 2(nd) MC-GARD series on "Interplay among genetics, epigenetics and non-coding RNAs".
• Cost-effectiveness of adding human papilloma virus testing to a managed care cervical cancer screening program.
• Effects of mothers' prenatal psychiatric status and postnatal caregiving on infant biobehavioral regulation: Can prenatal programming be modified?
• Identifying dynamical modules from genetic regulatory systems: applications to the segment polarity network.
• Influence of crystalloid and colloid replacement solutions on hemodynamic variables during acute normovolemic hemodilution.
• Injuries of the tibio-fibular ligaments.
• Personality correlates with sleep-wake variables.
• Practical consequences of fatigue-related performance failures.
• Pregnant women's cortisol is elevated with anxiety and depression - but only when comorbid.
• Prenatal predictors of infant temperament.
• Radiographic technique chart.
• Recognition of facial emotions among maltreated children with high rates of post-traumatic stress disorder.
• Regulative feedback in pattern formation: towards a general relativistic theory of positional information.
• Relationship between trait anxiety, prefrontal cortex, and attention bias to angry faces in children and adolescents.
• Single-cell analysis of unstable genes.
• Stress, immunity, and cervical cancer: biobehavioral outcomes of a randomized clinical trail.
• The Pediatrician's Role in Preventing Cervical Cancer.
• The construction of cDNA libraries from human single preimplantation embryos and their use in the study of gene expression during development.
• The flowering of systems approaches in plant and crop biology.
• The lingering death of the autopsy.
• Topical fluorouracil in vitiligo.
• Traumatic ischaemia of the calf.
• Type and severity of cognitive decline in older adults after noncardiac surgery.