Induction of immunoglobulin secretion in cultured human lymphocytes by 4 Staphylococcus aureus strains and their extracts. Abstract Text:
Human blood lymphocytes were stimulated in vitro by four Staphylococcus aureus strains. Activation of immunoglobulin-secreting cells was determined by a reverse plaque forming cell (PFC) assay, and proliferation by quantitation of thymidine incorporation. Whole killed S. aureus were slightly more efficient than water-soluble preparations in the form of sonicated extracts and culture supernatants. Two S. aureus strains rich in protein A (Cowan I and E 2371) and one S. aureus strain deficient in protein A (E 1369) were potent B-lymphocyte stimulators inducing maximal activity on day 6 of culture. Another S. aureus strain deficient in protein A (Wood 46) did not possess++ human lymphocyte stimulating capacity.
Induction of immunoglobulin secretion in cultured human lymphocytes by 4 Staphylococcus aureus strains and their extracts. Publishing Authors By Initials
Induction of immunoglobulin secretion in cultured human lymphocytes by 4 Staphylococcus aureus strains and their extracts. Journal Published:
PUBLICATION TYPE: Journal Article
Journal: Acta pathologica, microbiologica, et immunologica
VOLUME: 92
Page Numbers: 121-8
Journal Abbreviation:
ISSN: 0108-0202
DAY: 26
MONTH: Apr
YEAR: 1984
Induction of immunoglobulin secretion in cultured human lymphocytes by 4 Staphylococcus aureus strains and their extracts. Information
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LANGUAGE: eng
NlmUniqueID: 8206624
Induction of immunoglobulin secretion in cultured human lymphocytes by 4 Staphylococcus aureus strains and their extracts. Keywords Mesh Terms:
KEYWORDS: Tissue Extracts
MESH TERMS: immunology
Chemical & Substance for Abstract: Induction of immunoglobulin secretion in cultured human lymphocytes by 4 Staphylococcus aureus strains and their extracts. Information
Substance Name: Tissue Extracts
Registry Number: 0
Grant and Affiliation Information for Induction of immunoglobulin secretion in cultured human lymphocytes by 4 Staphylococcus aureus strains and their extracts.
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Country: DENMARK
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MEDLINETA: Acta Pathol Microbiol Immunol
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