Induced posterior vitreous detachment by intravitreal sulfur hexafluoride (SF6) injection in patients with nonproliferative diabetic retinopathy.

Induced posterior vitreous detachment by intravitreal sulfur hexafluoride (SF6) injection in patients with nonproliferative diabetic retinopathy. Research Abstract Details 

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Induced posterior vitreous detachment by intravitreal sulfur hexafluoride (SF6) injection in patients with nonproliferative diabetic retinopathy. Abstract Text:

PURPOSE: To induce posterior vitreous detachment (PVD) in patients with nonproliferative diabetic retinopathy (NPDR) by injecting an intravitreal gas bubble of SF6 and to compare the evolution of the diabetic retinopathy between eyes with gas induced PVD and non-injected eyes without PVD. METHODS: An intravitreal gas bubble of SF6 was injected via the pars plana in twelve eyes of twelve patients with NPDR and no previous PVD. Subsequent clinical, ultrasonographic and angiographic controls were performed to evaluate the development of PVD and progression of the disease. RESULTS: All gas-injected eyes developed PVD. All eyes with induced PVD (treatment group) remained stable without progression of the retinopathy after 2 years of follow up. In the control group (contralateral eyes without PVD), two eyes (16.6%) progressed to proliferative diabetic retinopathy (PDR) (p= 0.23); five (41.6%) showed progression to more severe stages of NPDR (p= 0.01) and another 41.6% of such eyes remained stable. CONCLUSIONS: Intravitreal SF6 injection induced PVD in all eyes of our study without undesirable side effects. Further studies are necessary to make conclusions regarding the correlation between the presence of induced PVD and the progression of diabetic retinopathy.

Induced posterior vitreous detachment by intravitreal sulfur hexafluoride (SF6) injection in patients with nonproliferative diabetic retinopathy. Publishing Authors By Initials

For similar eye diseases: vitreous detachment research abstracts see: eye diseases: vitreous detachment research

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Induced posterior vitreous detachment by intravitreal sulfur hexafluoride (SF6) injection in patients with nonproliferative diabetic retinopathy. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Acta ophthalmologica Scandinavica

VOLUME: 78

Page Numbers: 687-8

Journal Abbreviation: Acta Ophthalmol Scand

ISSN: 1395-3907

DAY: 17

MONTH: Dec

YEAR: 2000

Induced posterior vitreous detachment by intravitreal sulfur hexafluoride (SF6) injection in patients with nonproliferative diabetic retinopathy. Information

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LANGUAGE: eng

NlmUniqueID: 9507578

Induced posterior vitreous detachment by intravitreal sulfur hexafluoride (SF6) injection in patients with nonproliferative diabetic retinopathy. Keywords Mesh Terms:

KEYWORDS: Vitreous Detachment

MESH TERMS: physiopathology

Chemical & Substance for Abstract: Induced posterior vitreous detachment by intravitreal sulfur hexafluoride (SF6) injection in patients with nonproliferative diabetic retinopathy. Information

Substance Name: Sulfur Hexafluoride

Registry Number: 2551-62-4

Grant and Affiliation Information for Induced posterior vitreous detachment by intravitreal sulfur hexafluoride (SF6) injection in patients with nonproliferative diabetic retinopathy.

AFFILIATION: Asociación Para Evitar La Ceguera en México, Mexico City. retinamex@yahoo.com

Country: Denmark

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MEDLINETA: Acta Ophthalmol Scand

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