Independent design and conduct of clinical trials.

Independent design and conduct of clinical trials. Research Abstract Details 

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Independent design and conduct of clinical trials. Abstract Text:

Salim Yusuf,Jackie Bosch,Salim Yusuf,Jackie Bosch,

Randomized clinical trials (RCTs) have justifiably become the cornerstone for the evaluation of virtually any kind of intervention: drugs, surgical or diagnostic procedures, behavioural modifications, health policies and even systems of care. This commentary focuses on two issues related to independence in clinical trials: first, the independence to ask important questions, and second, independence from bias in the conduct, analysis and reporting of trials, which can lead to misleading conclusions. The most frequent type of RCT are those evaluating therapies, and much of this commentary will be focused on issues relevant to such trials, although the principles apply generally.

Independent design and conduct of clinical trials. Publishing Authors By Initials

S Yusuf,J Bosch,S Yusuf,J Bosch,

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Independent design and conduct of clinical trials. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Clinical trials (London, England)

VOLUME: 3

Page Numbers: 503-7

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ISSN: 1740-7745

DAY: 15

MONTH: 12

YEAR: 2006

Independent design and conduct of clinical trials. Information

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LANGUAGE: eng

NlmUniqueID: 101197451

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Grant and Affiliation Information for Independent design and conduct of clinical trials.

AFFILIATION: Department of Medicine, Division of Cardiology, McMaster University, Hamilton, Ontario, Canada, Population Health Research Institute, McMaster University, Hamilton, Ontario, Canada. yusufs@mcmaster.ca.

Country: England

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MEDLINETA: Clin Trials

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