[Incubation of Beef tRNALeu in interferon-treated cells lysate leads to a partial removal of the 3' terminal sequence (author's transl)]

[Incubation of Beef tRNALeu in interferon-treated cells lysate leads to a partial removal of the 3' terminal sequence (author's transl)] Research Abstract Details 

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[Incubation of Beef tRNALeu in interferon-treated cells lysate leads to a partial removal of the 3' terminal sequence (author's transl)] Abstract Text:

G Keith,M L Gangloff,R Falcoff,G Dirheimer,

Beef tRNALeu and tRNAArg labeled with [32P]-phosphate at their 3' hydroxyl or 5'-phosphate ends have been incubated in the presence of lysates of interferon-treated Mouse cells. The degradation of the two tRNAs has been followed by polyacrylamide slab gel electrophoresis. In all cases, the incubation leads to a degradation of the tRNAs to a variable extent, but tRNALeu is degraded much faster than tRNAArg. This study, provides evidence that the 3' terminal C - C - A is the primary target of degradation leading to a very fast inactivation of tRNALeu and to the inhibition of translation of exogenous and synthetic mRNAs.

[Incubation of Beef tRNALeu in interferon-treated cells lysate leads to a partial removal of the 3' terminal sequence (author's transl)] Publishing Authors By Initials

G Keith,ML Gangloff,R Falcoff,G Dirheimer,

For similar amino acids, peptides, and proteins: amino acids: rna, transfer, amino acyl research abstracts see: amino acids, peptides, and proteins: amino acids: rna, transfer, amino acyl research

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[Incubation of Beef tRNALeu in interferon-treated cells lysate leads to a partial removal of the 3' terminal sequence (author's transl)] Journal Published:

PUBLICATION TYPE: Research Support, Non-U.S. Gov

Journal: Comptes rendus des séances de l'Académie des scien

VOLUME: 294

Page Numbers: 795-8

Journal Abbreviation:

ISSN: 0249-6313

DAY: 3

MONTH: May

YEAR: 1982

[Incubation of Beef tRNALeu in interferon-treated cells lysate leads to a partial removal of the 3' terminal sequence (author's transl)] Information

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LANGUAGE: fre

NlmUniqueID: 8108553

[Incubation of Beef tRNALeu in interferon-treated cells lysate leads to a partial removal of the 3' terminal sequence (author's transl)] Keywords Mesh Terms:

KEYWORDS: RNA, Transfer, Amino Acyl

MESH TERMS: physiology

Chemical & Substance for Abstract: [Incubation of Beef tRNALeu in interferon-treated cells lysate leads to a partial removal of the 3' terminal sequence (author's transl)] Information

Substance Name: Interferons

Registry Number: 9008-11-1

Grant and Affiliation Information for [Incubation of Beef tRNALeu in interferon-treated cells lysate leads to a partial removal of the 3' terminal sequence (author's transl)]

AFFILIATION:

Country: FRANCE

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MEDLINETA: C R Seances Acad Sci III

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