Increasing hepatitis C virus-associated hepatocellular carcinoma mortality and aging: Long term trends in Japan.

Increasing hepatitis C virus-associated hepatocellular carcinoma mortality and aging: Long term trends in Japan. Research Abstract Details 

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Increasing hepatitis C virus-associated hepatocellular carcinoma mortality and aging: Long term trends in Japan. Abstract Text:

Naota Taura,Hiroshi Yatsuhashi,Keisuke Hamasaki,Kazuhiko Nakao,Manabu Daikoku,Toshihito Ueki,Koji Yano,Takehiro Matsumoto,Hiromi Ishibashi,Katsumi Eguchi,

BACKGROUND: The incidence of hepatocellular carcinoma (HCC) in Japan has been increasing. The aim of the study was to determine the epidemiological trends in HCC mortality in Japan. METHODS: We reviewed the medical records of all patients whose death was caused by liver disease between 1981 and 2000 at two hospitals. The courses of death were separated based on presence or absence of HCC when death ensued. Additionally, cohorts of patients with HCC were analyzed in 5-year time periods. RESULTS: The number of deaths from hepatitis C virus (HCV)-associated HCC steadily increased 2.6 times from 49 to 128 during observation period. The mean age at death from HCV-associated HCC from 1996 to 2000 was significantly higher than that in the period from 1981 to 1985 (p<0.0001). INTERPRETATION: Deaths from HCV-associated HCC increased from 1981 to 2000, consistent with the aging of the population in Japan.

Increasing hepatitis C virus-associated hepatocellular carcinoma mortality and aging: Long term trends in Japan. Publishing Authors By Initials

N Taura,H Yatsuhashi,K Hamasaki,K Nakao,M Daikoku,T Ueki,K Yano,T Matsumoto,H Ishibashi,K Eguchi,

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Increasing hepatitis C virus-associated hepatocellular carcinoma mortality and aging: Long term trends in Japan. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Hepatology research : the official journal of the

VOLUME: 34

Page Numbers: 130-4

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ISSN: 1386-6346

DAY: 19

MONTH: 01

YEAR: 2006

Increasing hepatitis C virus-associated hepatocellular carcinoma mortality and aging: Long term trends in Japan. Information

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LANGUAGE: eng

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AFFILIATION: Clinical Research Center, National Nagasaki Medical Center, Kubara 2-1001-1, Omura, Nagasaki 856-8562, Japan; The First Department of Internal Medicine, Nagasaki University School of Medicine, Sakamoto 1-7-1, Nagasaki 852-8501 Japan.

Country: Netherlands

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MEDLINETA: Hepatol Res

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