Increased renal sensitivity to aldosterone in the potassium-loaded rat.

Increased renal sensitivity to aldosterone in the potassium-loaded rat. Research Abstract Details 

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Increased renal sensitivity to aldosterone in the potassium-loaded rat. Abstract Text:

W R Adam,J W Funder,

1. The renal response to aldosterone (urinary sodium and potassium excretion) was determined in adrenalectomized rats previously fed either a high potassium diet or a control diet. High K+ rats showed an enhanced response to aldosterone at all doses tested. 2. This enhanced response to aldosterone required the presence of the adrenal glands during the induction period, could be suppressed by a high sodium intake, but could not be induced by a low sodium diet. 3. No difference between high K+ and control rats could be detected in renal mineralcorticoid receptors, assessed by both in vivo and in vitro binding of tritiated aldosterone. 4. The method of the induction, and the mechanism of the enhanced response, remain to be defined.

Increased renal sensitivity to aldosterone in the potassium-loaded rat. Publishing Authors By Initials

WR Adam,JW Funder,

For similar chlorides: sodium chloride research abstracts see: chlorides: sodium chloride research

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Increased renal sensitivity to aldosterone in the potassium-loaded rat. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Clinical science and molecular medicine. Supplemen

VOLUME: 3

Page Numbers: 315s-317s

Journal Abbreviation:

ISSN: 0144-4107

DAY: 12

MONTH: Dec

YEAR: 1976

Increased renal sensitivity to aldosterone in the potassium-loaded rat. Information

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LANGUAGE: eng

NlmUniqueID: 7907311

Increased renal sensitivity to aldosterone in the potassium-loaded rat. Keywords Mesh Terms:

KEYWORDS: Sodium Chloride

MESH TERMS: metabolism

Chemical & Substance for Abstract: Increased renal sensitivity to aldosterone in the potassium-loaded rat. Information

Substance Name: Sodium Chloride

Registry Number: 7647-14-5

Grant and Affiliation Information for Increased renal sensitivity to aldosterone in the potassium-loaded rat.

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Country: ENGLAND

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MEDLINETA: Clin Sci Mol Med Suppl

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