Increased occurrence of diabetes in people with ischemic cardiovascular disease and general and abdominal obesity.

Increased occurrence of diabetes in people with ischemic cardiovascular disease and general and abdominal obesity. Research Abstract Details 

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Increased occurrence of diabetes in people with ischemic cardiovascular disease and general and abdominal obesity. Abstract Text:

Gilles R Dagenais,Pierre Auger,Peter Bogaty,Hertzel Gerstein,Eva Lonn,Qilong Yi,Salim Yusuf, ,

BACKGROUND: Diabetes worsens the prognosis of patients with ischemic cardiovascular disease (ICVD). Increased body weight and abdominal obesity have been shown to increase the risk of diabetes in people without ICVD. Such a relationship has not been assessed in patients with ICVD who may have a different occurrence due to their disease and medications. OBJECTIVE: To examine the risk of developing diabetes among patients with ICVD according to body mass index (BMI), waist-to-hip ratio and waist circumference METHODS: Anthropometric measurements were done in 4699 men and 1187 women with ICVD (mean age 66 years) and without known diabetes at entry to the Heart Outcomes Prevention Evaluation (HOPE) study. During the median 4.5-year follow-up, a diagnosis of diabetes was reported in 261 (4.4%) participants. RESULTS: There was a positive and graded association between increased BMI, waist circumference and waist-to-hip ratio, and the risk of developing diabetes (P for trends <0.0001). After adjusting for all baseline characteristic differences including medications, the relative risk of developing diabetes after the first 40th percentile of each anthropometric measure increased by 12% (95% CI 9% to 15%) for every 1 kg/m2 increase in BMI; the relative risk increased by 5% (95% CI 4% to 6%) for every 1 cm increase in waist circumference and by 38% (95% CI 18% to 61%) for every 0.1 unit increase in waist-to-hip ratio. CONCLUSION: In patients with ICVD, increased BMI, waist-to-hip ratio and particularly waist circumference constitute independent risk factors for development of diabetes.

Increased occurrence of diabetes in people with ischemic cardiovascular disease and general and abdominal obesity. Publishing Authors By Initials

GR Dagenais,P Auger,P Bogaty,H Gerstein,E Lonn,Q Yi,S Yusuf, ,

For similar investigative techniques: epidemiologic methods: statistics as topic: probability: risk: risk factors research abstracts see: investigative techniques: epidemiologic methods: statistics as topic: probability: risk: risk factors research

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Increased occurrence of diabetes in people with ischemic cardiovascular disease and general and abdominal obesity. Journal Published:

PUBLICATION TYPE: Research Support, Non-U.S. Gov

Journal: The Canadian journal of cardiology

VOLUME: 19

Page Numbers: 1387-91

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ISSN: 1916-7075

DAY: 3

MONTH: Nov

YEAR: 2003

Increased occurrence of diabetes in people with ischemic cardiovascular disease and general and abdominal obesity. Information

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LANGUAGE: eng

NlmUniqueID: 8510280

Increased occurrence of diabetes in people with ischemic cardiovascular disease and general and abdominal obesity. Keywords Mesh Terms:

KEYWORDS: Risk Factors

MESH TERMS: epidemiology

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Grant and Affiliation Information for Increased occurrence of diabetes in people with ischemic cardiovascular disease and general and abdominal obesity.

AFFILIATION: Laval University Heart and Lung Institute, Ste-Foy, Quebec, Canada. dagenaisgetr@hotmail.com

Country: Canada

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MEDLINETA: Can J Cardiol

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