Increased mTORC1 signaling UPRegulates stress.

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Increased mTORC1 signaling UPRegulates stress. Abstract Text:

In this issue of Molecular Cell, Ozcan et al. (2008) show that the loss of the tuberous sclerosis tumor suppressor complex induces endoplasmic reticulum stress, leading to attenuation of insulin receptor signaling activity via the unfolded protein response.

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Increased mTORC1 signaling UPRegulates stress. Journal Published:

PUBLICATION TYPE: Research Support, Non-U.S. Gov

Journal: Molecular cell

VOLUME: 29

Page Numbers: 533-5

Journal Abbreviation: Mol. Cell

ISSN: 1097-4164

DAY: 14

MONTH: Mar

YEAR: 2008

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LANGUAGE: eng

NlmUniqueID: 9802571

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Grant and Affiliation Information for Increased mTORC1 signaling UPRegulates stress.

AFFILIATION: Whitehead Institute for Biomedical Research, 9 Cambridge Center, Cambridge, MA 02142, USA.

Country: United States

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MEDLINETA: Mol Cell

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