Increase of Metabolic Syndrome Score is an Independent Determinant of Increasing Pulse Pressure.

Increase of Metabolic Syndrome Score is an Independent Determinant of Increasing Pulse Pressure. Research Abstract Details 

Research Abstract Table of Contents

Jump to the:

Increase of Metabolic Syndrome Score is an Independent Determinant of Increasing Pulse Pressure. Abstract Text:

Jae-Youn Moon,Sungha Park,Chul Min Ahn,Jung Rae Cho,Chan Mi Park,Young-Guk Ko,Donghoon Choi,Myung Ho Jeong,Yangsoo Jang,Namsik Chung,

Purpose: The objective of this study was to determine whether the progressive increase of metabolic syndrome (MetS) score, the number of components of MetS, is correlated significantly with increasing pulse pressure (PP). Materials and Methods: 4,034 subjects were enrolled from the Cardiovascular Genome Center of Yonsei University (M:F=2344:1690, 55.2 +/- 10.5). Most of the study population were recruited from hypertension clinics, controlled with medications according to JNC7 guidelines. The Asian modified criteria of MetS were applied and MetS score was estimated. The HOMA index for insulin resistance, cholesterol profiles, and anthropometric measurements were assessed. Results: Among 4034 participants, 1690 (41.9%) were classified as MetS. Progressive increase in PP was demonstrated for increasing components of the MetS score. Multiple linear regression analysis with PP as the dependent variable showed that age (beta = 0.311, p < 0.001), MetS score (beta = 0.226, p < 0.001), male gender (beta = -0.093, p < 0.001) and HOMA index IR (beta = 0.033, p = 0.03) are significantly associated with PP (R(2) = 0.207, p < 0.001). Conclusion: The present results from this study demonstrate that increasing MetS score is an independent determinant of increasing PP. The results also demonstrate the independent role of MetS in increasing arterial stiffness and PP.

Increase of Metabolic Syndrome Score is an Independent Determinant of Increasing Pulse Pressure. Publishing Authors By Initials

JY Moon,S Park,CM Ahn,JR Cho,CM Park,YG Ko,D Choi,MH Jeong,Y Jang,N Chung,

For similar abstracts research abstracts see: abstracts research

PUBMED ID PMID:

MEDLINE DATE:

Increase of Metabolic Syndrome Score is an Independent Determinant of Increasing Pulse Pressure. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Yonsei medical journal

VOLUME: 49

Page Numbers: 63-70

Journal Abbreviation: Yonsei Med. J.

ISSN: 0513-5796

DAY: 28

MONTH: Feb

YEAR: 2008

Increase of Metabolic Syndrome Score is an Independent Determinant of Increasing Pulse Pressure. Information

Number of References:

LANGUAGE: eng

NlmUniqueID: 414003

Increase of Metabolic Syndrome Score is an Independent Determinant of Increasing Pulse Pressure. Keywords Mesh Terms:

KEYWORDS:

MESH TERMS:

Chemical & Substance for Abstract: Increase of Metabolic Syndrome Score is an Independent Determinant of Increasing Pulse Pressure. Information

Substance Name:

Registry Number:

Grant and Affiliation Information for Increase of Metabolic Syndrome Score is an Independent Determinant of Increasing Pulse Pressure.

AFFILIATION: Division of Cardiology, Yonsei Cardiovascular Center, Yonsei University College of Medicine, 250 Seongsanno, Seodaemun-gu, Seoul 120-752, Korea. shpark0530@yuhs.ac.

Country: Korea (South)

AGENCY:

GRANT:

ACRONYM:

MEDLINETA: Yonsei Med J

REFSOURCE:

DATABASENAME:

ACCESSION NUMBER:

Number Hits: 0

Increase of Metabolic Syndrome Score is an Independent Determinant of Increasing Pulse Pressure Related Publications

• A 2-year open-label study of galantamine therapy in Chinese Alzheimer's disease patients in Hong Kong.
• Blockade of apoptosis as a rational therapeutic strategy for the treatment of sepsis.
• Characterization of a core binding site for ADAMTS-13 in the A2 domain of von Willebrand factor.
• Distribution of respiratory mucin proteins in human nasal mucosa.
• Effect of superoxide dismutase on the development of preimplantation mouse embryos.
• Estrogens and antiestrogens as etiological factors and therapeutics for prostate cancer.
• Experience of Middle- and Old-Aged Women's Aging.
• Expression of MUC5AC and MUC5B mucins in normal and cystic fibrosis lung.
• Expression of respiratory mucins in fatal status asthmaticus and mild asthma.
• Honokiol, a natural plant product, inhibits the bone metastatic growth of human prostate cancer cells.
• IGF-1 protects intestinal epithelial cells from oxidative stress-induced apoptosis.
• Importance of hyperexcitability of DRG neurons in neuropathic pain.
• Improved results using extensively coated THA stems at minimum 5-year followup.
• Inhibition of transforming growth factor-beta/Smad signaling by phosphatidylinositol 3-kinase pathway.
• MYCN silencing induces differentiation and apoptosis in human neuroblastoma cells.
• Mucus and fatal asthma.
• Oxidative stress induces ADAM9 protein expression in human prostate cancer cells.
• Oxidative stress-induced intestinal epithelial cell apoptosis is mediated by p38 MAPK.
• Pellegrini-Stieda disease: a heterogeneous disorder not synonymous with ossification/calcification of the tibial collateral ligament-anatomic and imaging investigation.
• Postnatal depression: an update.
• Role of RacC for the regulation of WASP and phosphatidylinositol 3-kinase during chemotaxis of Dictyostelium.
• The WPA Regional Meeting "Science and Humanism" (Seoul, April 18-21, 2007).
• The clinical implementation of respiratory-gated intensity-modulated radiotherapy.
• The role of reactive oxygen species (ROS) in persistent pain.
• Using the PHQ-9 for depression screening and treatment monitoring for Chinese Americans in primary care.
• Vanadium-catalyzed addition of propargyl alcohols and imines.
• [Development of a critical thinking disposition scale for nursing students]
• [Massive gastric ulcer bleeding in a healthy full term infant]
• [Modulation of tropoelastin expression in cultured human dermal fibroblasts by heat shock.]
• [Resistance to adefovir in patients with chronic hepatitis B]