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Incorporating hematopoietic cell transplantation (HCT) into the management of adults aged under 60 years with acute myeloid leukemia (AML).

Incorporating hematopoietic cell transplantation (HCT) into the management of adults aged under 60 years with acute myeloid leukemia (AML). Research Abstract Details 

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  • Incorporating hematopoietic cell transplantation (HCT) into the management of adults aged under 60 years with acute myeloid leukemia (AML). Abstract Text:

    Current strategies for incorporating hematopoietic cell transplantation into the treatment of adults with AML are based predominantly on pre-treatment patient, donor and disease characteristics. These strategies, while useful, have significant shortcomings in that they recommend deferred transplantation for many patients who would benefit from earlier intervention and, at the same time, direct other patients who would be cured with chemotherapy alone to the more risky and toxic approach of early transplantation. Here we review the currently accepted indications for transplantation and raise the possibility that alternative approaches to incorporating transplantation into the management of adults with AML that rely predominantly on the measurement of minimal residual disease (MRD) could save additional lives without any major advance in chemotherapy or transplant technologies.

    Incorporating hematopoietic cell transplantation (HCT) into the management of adults aged under 60 years with acute myeloid leukemia (AML). Publishing Authors By Initials

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    PUBMED ID PMID:

    MEDLINE DATE:

    Incorporating hematopoietic cell transplantation (HCT) into the management of adults aged under 60 years with acute myeloid leukemia (AML). Journal Published:

    PUBLICATION TYPE: Journal Article

    Journal: Best practice & research. Clinical haematology

    VOLUME: 21

    Page Numbers: 85-92

    Journal Abbreviation:

    ISSN: 1521-6926

    DAY: 17

    MONTH: Mar

    YEAR: 2008

    Incorporating hematopoietic cell transplantation (HCT) into the management of adults aged under 60 years with acute myeloid leukemia (AML). Information

    Number of References:

    LANGUAGE: eng

    NlmUniqueID: 101120659

    Incorporating hematopoietic cell transplantation (HCT) into the management of adults aged under 60 years with acute myeloid leukemia (AML). Keywords Mesh Terms:

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    Grant and Affiliation Information for Incorporating hematopoietic cell transplantation (HCT) into the management of adults aged under 60 years with acute myeloid leukemia (AML).

    AFFILIATION: Fred Hutchinson Cancer Research Center, Clinical Research Division, 1100 Fairview Avenue North, D5-310, P.O. Box 19024, Seattle, WA 98109-1024, USA; Division of Oncology, University of Washington, Seattle, WA, USA.

    Country: England

    England Research PublicationEngland Research Publication

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    MEDLINETA: Best Pract Res Clin Haematol

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