Incidental thyroid carcinoma in patients with Graves' disease.

Incidental thyroid carcinoma in patients with Graves' disease. Research Abstract Details 

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Incidental thyroid carcinoma in patients with Graves' disease. Abstract Text:

BACKGROUND: The clinical significance of incidental thyroid carcinoma in patients with Graves' disease is uncertain. METHODS: The prevalence of incidental thyroid carcinoma was determined in patients with Graves' disease who underwent surgery from 1990 to 2007 and was compared with patients with nontoxic nodular goiter or toxic multinodular goiter who underwent surgery during the same time period. RESULTS: Of the 93 patients who underwent thyroidectomy for Graves' disease, 2 patients (2.2%) had an incidental papillary carcinoma: .4 and .5 cm in size. Neither patient developed recurrent disease after 3 and 13 years of follow-up evaluation. The prevalence of incidental thyroid cancer was 3.6% and 6.2% in patients with nontoxic nodular goiter and toxic multinodular goiter, respectively (P = not significant). CONCLUSIONS: The prevalence of incidental thyroid carcinoma in patients with Graves' disease is comparable with patients with nontoxic or toxic goiter. Incidental thyroid carcinomas in patients with Graves' disease were papillary microcarcinomas of no clinical consequence.

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Incidental thyroid carcinoma in patients with Graves' disease. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: American journal of surgery

VOLUME: 195

Page Numbers: 292-7

Journal Abbreviation: Am. J. Surg.

ISSN: 0002-9610

DAY: 29

MONTH: Mar

YEAR: 2008

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LANGUAGE: eng

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AFFILIATION: Department of Surgery, MetroHealth Medical Center, Case Western Reserve University School of Medicine, 2500 MetroHealth Dr., Cleveland, OH 44109, USA.

Country: United States

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MEDLINETA: Am J Surg

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