Incidence of local recurrence and port site metastasis after laparoscopic radical nephroureterectomy.

Incidence of local recurrence and port site metastasis after laparoscopic radical nephroureterectomy. Research Abstract Details 

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Incidence of local recurrence and port site metastasis after laparoscopic radical nephroureterectomy. Abstract Text:

Michael Muntener,Edward M Schaeffer,Frederico R Romero,Matthew E Nielsen,Mohamad E Allaf,Fabio Augusto R Brito,Christian P Pavlovich,Louis R Kavoussi,Thomas W Jarrett,Michael Muntener,Edward M Schaeffer,Frederico R Romero,Matthew E Nielsen,Mohamad E Allaf,Fabio Augusto R Brito,Christian P Pavlovich,Louis R Kavoussi,Thomas W Jarrett,

OBJECTIVES: To address the incidence of local recurrence and port site metastasis in patients who underwent laparoscopic radical nephroureterectomy (RNU) for upper tract transitional cell carcinoma (TCC). METHODS: Between August 1993 and February 2006 116 laparoscopic RNU were performed in 115 patients at our institution. A traditional open excision, a laparoscopic stapler resection or a different approach was used for the management of the distal ureter in 76, 27, and 11 cases, respectively. Clinical follow-up as well as perioperative and pathologic data were retrospectively collected. RESULTS: Perioperative and pathologic data were available in all 116 cases. Clinical outcomes were available in 107 patients with a mean follow-up of 30.5 months (range 1 to 148). Six patients (5.6%) had a local recurrence develop, including 1 patient with port site metastasis (0.9%) at an average of 5.7 months. In 2 of these patients, violation of the ipsilateral urinary tract was noted perioperatively. CONCLUSIONS: We report, in this large single-center series of laparoscopic RNU, a low incidence of local recurrence. Our results confirm that a laparoscopic approach to upper tract TCC does not result in a clinically significant increased risk of tumor spillage provided that principles of oncologic surgery are followed.

Incidence of local recurrence and port site metastasis after laparoscopic radical nephroureterectomy. Publishing Authors By Initials

M Muntener,EM Schaeffer,FR Romero,ME Nielsen,ME Allaf,FA Brito,CP Pavlovich,LR Kavoussi,TW Jarrett,M Muntener,EM Schaeffer,FR Romero,ME Nielsen,ME Allaf,FA Brito,CP Pavlovich,LR Kavoussi,TW Jarrett,

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Incidence of local recurrence and port site metastasis after laparoscopic radical nephroureterectomy. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Urology

VOLUME: 70

Page Numbers: 864-8

Journal Abbreviation: Urology

ISSN: 1527-9995

DAY: 10

MONTH: Nov

YEAR: 2007

Incidence of local recurrence and port site metastasis after laparoscopic radical nephroureterectomy. Information

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LANGUAGE: eng

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AFFILIATION: The James Buchanan Brady Urological Institute, The Johns Hopkins Medical Institutions, Baltimore, Maryland 21287-2101, USA. muntener@jhmi.edu

Country: United States

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MEDLINETA: Urology

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