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In vivo ultrahigh-resolution optical coherence tomography.

In vivo ultrahigh-resolution optical coherence tomography. Research Abstract Details 

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  • In vivo ultrahigh-resolution optical coherence tomography. Abstract Text:

    w drexlerW Drexler,u morgnerU Morgner,f x F X ,c pitrisC Pitris,s a boppartS A Boppart,x d liX D Li,e p ippenE P Ippen,j g fujimotoJ G Fujimoto,

    Ultrahigh-resolution optical coherence tomography (OCT) by use of state of the art broad-bandwidth femtosecond laser technology is demonstrated and applied to in vivo subcellular imaging. Imaging is performed with a Kerr-lens mode-locked Ti:sapphire laser with double-chirped mirrors that emits sub-two-cycle pulses with bandwidths of up to 350 nm, centered at 800 nm. Longitudinal resolutions of ~1mum and transverse resolution of 3mum, with a 110-dB dynamic range, are achieved in biological tissue. To overcome depth-of-field limitations we perform zone focusing and image fusion to construct a tomogram with high transverse resolution throughout the image depth. To our knowledge this is the highest longitudinal resolution demonstrated to date for in vivo OCT imaging.

    In vivo ultrahigh-resolution optical coherence tomography. Publishing Authors By Initials

    w drexlerW Drexler,u morgnerU Morgner,fx FX ,c pitrisC Pitris,sa boppartSA Boppart,xd liXD Li,ep ippenEP Ippen,jg fujimotoJG Fujimoto,

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    PUBMED ID PMID:

    MEDLINE DATE:

    In vivo ultrahigh-resolution optical coherence tomography. Journal Published:

    PUBLICATION TYPE: Journal Article

    Journal: Optics letters

    VOLUME: 24

    Page Numbers: 1221-3

    Journal Abbreviation:

    ISSN: 0146-9592

    DAY: 1

    MONTH: Sep

    YEAR: 1999

    In vivo ultrahigh-resolution optical coherence tomography. Information

    Number of References:

    LANGUAGE: eng

    NlmUniqueID: 7708433

    In vivo ultrahigh-resolution optical coherence tomography. Keywords Mesh Terms:

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    Chemical & Substance for Abstract: In vivo ultrahigh-resolution optical coherence tomography. Information

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    Grant and Affiliation Information for In vivo ultrahigh-resolution optical coherence tomography.

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    Country: United States

    United States Research PublicationUnited States Research Publication

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    MEDLINETA: Opt Lett

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