In vivo observations of a case of chlorpromazine deposits in the cornea using an HRT II Rostock corneal module.

In vivo observations of a case of chlorpromazine deposits in the cornea using an HRT II Rostock corneal module. Research Abstract Details 

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In vivo observations of a case of chlorpromazine deposits in the cornea using an HRT II Rostock corneal module. Abstract Text:

Hiroshi Toshida,Yuko Uesugi,Nobuyuki Ebihara,Akira Murakami,Hiroshi Toshida,Yuko Uesugi,Nobuyuki Ebihara,Akira Murakami,

PURPOSE: In vivo study of corneal deposits in a patient receiving chlorpromazine therapy was done by using a confocal microscope, the HRT II Rostock corneal module (RCM). METHODS: A 23-year-old woman who had been on chlorpromazine therapy for 5 years complained of bilateral photophobia and was referred to our clinic. She had suffered from light sensitivity for 4 years. RESULTS: Slit-lamp microscopy revealed white deposits, particularly in the layers of the endothelium and Descemet membrane, which were concentrated in the center of both corneas. Deposition of many white granules was observed in the superficial subepithelial stroma of the cornea by HRT II RCM. Granular deposits were observed at the center of most cells in the corneal endothelium. CONCLUSIONS: The HRT II RCM could clearly detect deposits in the corneal endothelium, as well as in other regions such as the corneal epithelium and stroma.

In vivo observations of a case of chlorpromazine deposits in the cornea using an HRT II Rostock corneal module. Publishing Authors By Initials

H Toshida,Y Uesugi,N Ebihara,A Murakami,H Toshida,Y Uesugi,N Ebihara,A Murakami,

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In vivo observations of a case of chlorpromazine deposits in the cornea using an HRT II Rostock corneal module. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Cornea

VOLUME: 26

Page Numbers: 1141-3

Journal Abbreviation: Cornea

ISSN: 0277-3740

DAY: 25

MONTH: Oct

YEAR: 2007

In vivo observations of a case of chlorpromazine deposits in the cornea using an HRT II Rostock corneal module. Information

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LANGUAGE: eng

NlmUniqueID: 8216186

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AFFILIATION: Department of Ophthalmology, Juntendo University School of Medicine, Tokyo, Japan. toshida@med.juntendo.ac.jp

Country: United States

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MEDLINETA: Cornea

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