In vitro heart valve tissue engineering.

In vitro heart valve tissue engineering. Research Abstract Details 

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In vitro heart valve tissue engineering. Abstract Text:

Schmidt,Anita Mol,Jens M Kelm,Simon P Hoerstrup, Schmidt,Anita Mol,Jens M Kelm,Simon P Hoerstrup,

Heart valve replacement represents the most common surgical therapy for end-stage valvular heart diseases. A major drawback all contemporary heart valve replacements have in common is the lack of growth, repair, and remodeling capabilities. To overcome these limitations, the emerging field of tissue engineering is focusing on the in vitro generation of functional, living heart valve replacements. The basic approach uses starter matrices of either decellularized xenogeneic or biopolymeric materials configured in the shape of the heart valve and subsequent cell seeding. Moreover, in vitro strategies using mechanical loading in bioreactor systems have been developed to improve tissue maturation. This chapter gives a short overview of the current concepts and provides detailed methods for in vitro heart valve tissue engineering.

In vitro heart valve tissue engineering. Publishing Authors By Initials

D Schmidt,A Mol,JM Kelm,SP Hoerstrup,D Schmidt,A Mol,JM Kelm,SP Hoerstrup,

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In vitro heart valve tissue engineering. Journal Published:

PUBLICATION TYPE: Research Support, Non-U.S. Gov

Journal: Methods in molecular medicine

VOLUME: 140

Page Numbers: 319-30

Journal Abbreviation: Methods Mol. Med.

ISSN: 1543-1894

DAY: 18

MONTH: 12

YEAR: 2007

In vitro heart valve tissue engineering. Information

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LANGUAGE: eng

NlmUniqueID: 101123138

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Grant and Affiliation Information for In vitro heart valve tissue engineering.

AFFILIATION: Clinic of Cardiovascular Surgery, Zurich University Hospital, Switzerland.

Country: United States

AGENCY: United States NHLBI

GRANT: R01 HL076485-01

ACRONYM: HL

MEDLINETA: Methods Mol Med

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