In vitro discrimination of tumor cell lines with an electronic nose.

In vitro discrimination of tumor cell lines with an electronic nose. Research Abstract Details 

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In vitro discrimination of tumor cell lines with an electronic nose. Abstract Text:

Kristin B Gendron,Neil G Hockstein,Erica R Thaler,Anil Vachani,C William Hanson,

OBJECTIVE: The electronic nose is a sensor of volatile molecules that is useful in the analysis of expired gases. Our hypothesis is that the electronic nose can distinguish between different types of upper aerodigestive tract tumor cells in vitro. STUDY DESIGN: Cells from both tumor and normal cell lines were suspended in saline, and a polymer composite electronic nose was used to evaluate the headspace gases. The data were subjected to principal components analysis, and Mahalanobis distances were calculated to demonstrate the ability of the electronic nose to distinguish among samples. RESULTS: The tumor cell lines, including adenocarcinoma, squamous cell carcinoma, and mesothelioma, were distinct from each other, and from the normal fibroblast and smooth muscle cells as seen on canonical discrimination plots. CONCLUSION: The electronic nose can distinguish between tumor cell lines in vitro and has the potential to be a useful screening test for cancer.

In vitro discrimination of tumor cell lines with an electronic nose. Publishing Authors By Initials

KB Gendron,NG Hockstein,ER Thaler,A Vachani,CW Hanson,

For similar natural sciences: chemistry: chemistry, physical: phase transition: volatilization research abstracts see: natural sciences: chemistry: chemistry, physical: phase transition: volatilization research

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In vitro discrimination of tumor cell lines with an electronic nose. Journal Published:

PUBLICATION TYPE: Research Support, N.I.H., Extr

Journal: Otolaryngology--head and neck surgery : official j

VOLUME: 137

Page Numbers: 269-73

Journal Abbreviation:

ISSN: 0194-5998

DAY: 3

MONTH: Aug

YEAR: 2007

In vitro discrimination of tumor cell lines with an electronic nose. Information

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LANGUAGE: eng

NlmUniqueID: 8508176

In vitro discrimination of tumor cell lines with an electronic nose. Keywords Mesh Terms:

KEYWORDS: Volatilization

MESH TERMS: instrumentation

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Grant and Affiliation Information for In vitro discrimination of tumor cell lines with an electronic nose.

AFFILIATION: Department of Otorhinolaryngology--Head and Neck Surgery, University of Pennsylvania Health System, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA.

Country: United States

AGENCY: United States NCI

GRANT: K12CA076931-08

ACRONYM: CA

MEDLINETA: Otolaryngol Head Neck Surg

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