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In vitro and in vivo biocompatibility of graded hydroxyapatite-zirconia composite bioceramic.

In vitro and in vivo biocompatibility of graded hydroxyapatite-zirconia composite bioceramic. Research Abstract Details 

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  • In vitro and in vivo biocompatibility of graded hydroxyapatite-zirconia composite bioceramic. Abstract Text:

    renfu quanRenfu Quan,disheng yangDisheng Yang,xiaochun wuXiaochun Wu,hongbin wangHongbin Wang,xudong miaoXudong Miao,wei liWei Li,renfu quanRenfu Quan,disheng yangDisheng Yang,xiaochun wuXiaochun Wu,hongbin wangHongbin Wang,xudong miaoXudong Miao,wei liWei Li,

    To obtain bioceramics with good osteoinductive ability and mechanical strength, graded hydroxyapatite-zirconia (HA-ZrO(2)) composite bioceramics were prepared in this work. The biocompatibility of the bioceramics was investigated in vitro based on acute toxicity and cytotoxicity tests and hemolysis assay. Results showed the studied graded HA-ZrO(2) had little toxicity to mouse and L929 mouse fibroblasts. Also, hemolysis assay indicated a good blood compatibility of the bioceramics. Based on the results of in vitro tests, animal experiments were performed on white New Zealand rabbits by implantation into hip muscles and femur. It was found that the graded HA-ZrO(2) composite bioceramics exhibited superior osteoinductive ability, which may be a promising bioceramics implant.

    In vitro and in vivo biocompatibility of graded hydroxyapatite-zirconia composite bioceramic. Publishing Authors By Initials

    r quanR Quan,d yangD Yang,x wuX Wu,h wangH Wang,x miaoX Miao,w liW Li,r quanR Quan,d yangD Yang,x wuX Wu,h wangH Wang,x miaoX Miao,w liW Li,

    For similar abstracts research abstracts see: abstracts research

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    In vitro and in vivo biocompatibility of graded hydroxyapatite-zirconia composite bioceramic. Journal Published:

    PUBLICATION TYPE: Journal Article

    Journal: Journal of materials science. Materials in medicin

    VOLUME: 19

    Page Numbers: 183-7

    Journal Abbreviation:

    ISSN: 0957-4530

    DAY: 28

    MONTH: 06

    YEAR: 2007

    In vitro and in vivo biocompatibility of graded hydroxyapatite-zirconia composite bioceramic. Information

    Number of References:

    LANGUAGE: eng

    NlmUniqueID: 9013087

    In vitro and in vivo biocompatibility of graded hydroxyapatite-zirconia composite bioceramic. Keywords Mesh Terms:

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    Grant and Affiliation Information for In vitro and in vivo biocompatibility of graded hydroxyapatite-zirconia composite bioceramic.

    AFFILIATION: Department of Orthopaedics, Second Affiliated Hospital, Zhejiang University, Jiefang Road 88#, Hangzhou, 310009, China, quanrenfu8@yahoo.com.

    Country: United States

    United States Research PublicationUnited States Research Publication

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    MEDLINETA: J Mater Sci Mater Med

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