Nanoporous silica nanofibers have been employed as a matrix to encapsulate horseradish peroxide enzymes via a simple electrospinning method. A viscous solution of prehydrolyzed tetramethyl orthosilicate, beta-d-glucose, poly(vinyl alcohol), and enzymes were employed as spinning solution to generate porous fibers in the form of nonwoven mats. The silica fiber mats thus produced have a high surface area because of the small diameter (100 to 200 nm) of the fibers as well as the extreme porosity (2 to 4 nm) of individual fibers caused by the glucose template present in them. The high surface area, mechanical flexibility, thermal stability, reusability, and freedom of encapsulating various enzymes make porous silica nanofibers excellent biosensors.
In situ encapsulation of horseradish peroxidase in electrospun porous silica fibers for potential biosensor applications. Publishing Authors By Initials
In situ encapsulation of horseradish peroxidase in electrospun porous silica fibers for potential biosensor applications. Journal Published:
PUBLICATION TYPE: Research Support, U.S. Gov't,
Journal: Nano letters
VOLUME: 6
Page Numbers: 1042-6
Journal Abbreviation: Nano Lett.
ISSN: 1530-6984
DAY: 10
MONTH: May
YEAR: 2006
In situ encapsulation of horseradish peroxidase in electrospun porous silica fibers for potential biosensor applications. Information
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LANGUAGE: eng
NlmUniqueID: 101088070
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Grant and Affiliation Information for In situ encapsulation of horseradish peroxidase in electrospun porous silica fibers for potential biosensor applications.
AFFILIATION: Department of Chemistry, Drexel University, Philadelphia, Pennsylvania 19104, USA.
Country: United States
AGENCY: United States NIDCR
GRANT: DE09848
ACRONYM: DE
MEDLINETA: Nano Lett
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