In search of the fusion pore of exocytosis.

In search of the fusion pore of exocytosis. Research Abstract Details 

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In search of the fusion pore of exocytosis. Abstract Text:

Meyer B Jackson,

Research on calcium-triggered exocytosis has converged on the fusion pore as a critical kinetic intermediate. Using sensitive biophysical methods to record signals from living cells in the act of releasing neurotransmitter or hormone has provided clues about the structure and composition of fusion pores. The dynamics of fusion pore opening, closing, and dilating has revealed how specific proteins transduce a calcium binding signal to catalyze membrane fusion. The fusion pore determines how rapidly neurotransmitter is expelled from a vesicle into the synaptic cleft. This rate places constraints on the form of a synaptic response during different modes of release.

In search of the fusion pore of exocytosis. Publishing Authors By Initials

MB Jackson,

For similar synaptic transmission research abstracts see: synaptic transmission research

PUBMED ID PMID:

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In search of the fusion pore of exocytosis. Journal Published:

PUBLICATION TYPE: Review

Journal: Biophysical chemistry

VOLUME: 126

Page Numbers: 201-8

Journal Abbreviation: Biophys. Chem.

ISSN: 0301-4622

DAY: 22

MONTH: 06

YEAR: 2006

In search of the fusion pore of exocytosis. Information

Number of References: 41

LANGUAGE: eng

NlmUniqueID: 403171

In search of the fusion pore of exocytosis. Keywords Mesh Terms:

KEYWORDS: Synaptic Transmission

MESH TERMS: ultrastructure

Chemical & Substance for Abstract: In search of the fusion pore of exocytosis. Information

Substance Name: Calcium

Registry Number: 7440-70-2

Grant and Affiliation Information for In search of the fusion pore of exocytosis.

AFFILIATION: Department of Physiology, University of Wisconsin, Wisconsin, USA. mjackson@physiology.wisc.edu

Country: Netherlands

AGENCY: United States NINDS

GRANT: NS44057

ACRONYM: NS

MEDLINETA: Biophys Chem

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