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Improving treatment of late life depression in primary care: a randomized clinical trial.

Improving treatment of late life depression in primary care: a randomized clinical trial. Research Abstract Details 

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  • Improving treatment of late life depression in primary care: a randomized clinical trial. Abstract Text:

    OBJECTIVE: Facilitate primary care physicians' compliance with recommended standards of care for late life depression by reducing barriers to recognition and treatment. DESIGN: Randomized controlled clinical trial of physician-targeted interventions. SETTING: Academic primary care group practice caring for an urban, medically indigent patient population. PATIENTS/PARTICIPANTS: Patients aged 60 and older who exceeded the threshold on the Centers for Epidemiologic Studies Depression Scale (CES-D) and the Hamilton Depression Rating Scale (HAM-D) and their primary care physicians. INTERVENTION: Physicians of intervention patients were provided with patient-specific treatment recommendations during 3 special visits scheduled specifically to address the patient's symptoms of depression. In general, physicians were encouraged to establish a diagnosis of depression and educate their patient about the diagnosis, discontinue medications that can cause or exacerbate depressive symptoms, initiate antidepressants when appropriate, and consider referral to psychiatry. Guidelines for prescribing antidepressants were provided. Control physicians received no intervention, and control patients received usual care. MAIN OUTCOME MEASURES: Frequency of recording a depression diagnosis, stopping medications associated with depression, initiating antidepressant medication, and psychiatry referral; mean changes in HAM-D and Sickness Impact Profile (SIP) scores. RESULTS: One hundred three physicians and 175 patients were involved in the clinical trial. Physicians of intervention patients were more likely to diagnose depression and prescribe antidepressants (P < 0.01). There were no differences between the groups in the frequency of stopping medications associated with depression or referrals to psychiatry. Medications with the strongest cause and effect relationship to depression were infrequently used in this cohort of patients. Although both groups showed improvement in HAM-D and SIP scores, we were unable to demonstrate significant differences in HAM-D or SIP scores between the 2 groups. CONCLUSIONS: Intensive screening and feedback of patient-specific treatment recommendations increased the recognition and treatment of late life depression by primary care physicians. However, we were unable to demonstrate significant improvement in depression or disability severity among intervention patients despite the informational support provided to their physicians. Efforts to improve the functional status of these patients may require more integrated interventions and more aggressive attempts to target psychosocial stressors traditionally outside the purview of primary care.

    Improving treatment of late life depression in primary care: a randomized clinical trial. Publishing Authors By Initials

    For similar organization and administration: professional practice: referral and consultation research abstracts see: organization and administration: professional practice: referral and consultation research

    PUBMED ID PMID:

    MEDLINE DATE:

    Improving treatment of late life depression in primary care: a randomized clinical trial. Journal Published:

    PUBLICATION TYPE: Research Support, Non-U.S. Gov

    Journal: Journal of the American Geriatrics Society

    VOLUME: 42

    Page Numbers: 839-46

    Journal Abbreviation: J Am Geriatr Soc

    ISSN: 0002-8614

    DAY: 10

    MONTH: Aug

    YEAR: 1994

    Improving treatment of late life depression in primary care: a randomized clinical trial. Information

    Number of References:

    LANGUAGE: eng

    NlmUniqueID: 7503062

    Improving treatment of late life depression in primary care: a randomized clinical trial. Keywords Mesh Terms:

    KEYWORDS: Referral and Consultation

    MESH TERMS: psychology

    Chemical & Substance for Abstract: Improving treatment of late life depression in primary care: a randomized clinical trial. Information

    Substance Name: Antidepressive Agents

    Registry Number: 0

    Grant and Affiliation Information for Improving treatment of late life depression in primary care: a randomized clinical trial.

    AFFILIATION: Department of Medicine, Indiana University School of Medicine, Regenstrief Institute for Health Care, Indianapolis 46202-2859.

    Country: UNITED STATES

    UNITED STATES Research PublicationUNITED STATES Research Publication

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    ACRONYM:

    MEDLINETA: J Am Geriatr Soc

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