The aim of this study is to report a possible implication of augmented vasogenic leakage in the mechanism of prolonged aura in sporadic hemiplegic migraine. A 35-year-old woman with sporadic hemiplegic migraine presented with headache followed by right arm weakness, right visual field defect, aphasia and confusion that persisted for 1 week. During the acute stage, focal hyperaemia was seen in the left cerebral hemisphere corresponding to persistent aura symptoms. Augmented vasogenic leakage was demonstrated on delayed enhanced fluid-attenuated inversion recovery image. Magnetic resonance angiography showed dilation of the left middle cerebral artery. During the convalescent stage, such abnormal findings were not seen. Based on these results, we speculate that augmented vasogenic leakage from the leptomeningeal vessels, probably associated with activation of the trigeminovascular system, may delay the recovery of hemiplegic migraine aura.
Implication of augmented vasogenic leakage in the mechanism of persistent aura in sporadic hemiplegic migraine. Publishing Authors By Initials
Implication of augmented vasogenic leakage in the mechanism of persistent aura in sporadic hemiplegic migraine. Journal Published:
PUBLICATION TYPE: Research Support, Non-U.S. Gov
Journal: Cephalalgia : an international journal of headache
VOLUME: 26
Page Numbers: 332-5
Journal Abbreviation: Cephalalgia
ISSN: 0333-1024
DAY: 11
MONTH: Mar
YEAR: 2006
Implication of augmented vasogenic leakage in the mechanism of persistent aura in sporadic hemiplegic migraine. Information
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LANGUAGE: eng
NlmUniqueID: 8200710
Implication of augmented vasogenic leakage in the mechanism of persistent aura in sporadic hemiplegic migraine. Keywords Mesh Terms:
KEYWORDS: Vision Disorders
MESH TERMS: physiopathology
Chemical & Substance for Abstract: Implication of augmented vasogenic leakage in the mechanism of persistent aura in sporadic hemiplegic migraine. Information
Substance Name: Adrenal Cortex Hormones
Registry Number: 0
Grant and Affiliation Information for Implication of augmented vasogenic leakage in the mechanism of persistent aura in sporadic hemiplegic migraine.
AFFILIATION: Department of Neurology, School of Medicine, Kitasato University, Kanagawa, Japan. takahiro@med.kitasato-u.ac.jp
Country: England
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MEDLINETA: Cephalalgia
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