Impaired parathyroid hormone response to hypocalcemic stimuli in a patient with hypomagnesemic hypocalcemia.

Impaired parathyroid hormone response to hypocalcemic stimuli in a patient with hypomagnesemic hypocalcemia. Research Abstract Details 

Research Abstract Table of Contents

Jump to the:

Impaired parathyroid hormone response to hypocalcemic stimuli in a patient with hypomagnesemic hypocalcemia. Abstract Text:

Y Iwasaki,M Asai,M Yoshida,Y Oiso,K Hashimoto,

Magnesium (Mg) deficiency sometimes causes hypocalcemia with impaired PTH secretion although the precise mechanism remains unclear. We examined the PTH secretion in response to physiological hypocalcemic stimuli in a patient with hypomagnesemic hypocalcemia. We adopted sodium bicarbonate infusion test, which we recently developed, to evaluate the PTH response to acute decrease in plasma ionized Ca. The results showed that, before Mg replacement and when the patient was mildly hypocalcemic, absolutely no PTH release to hypocalcemic stimuli was observed. In contrast, the plasma Ca was promptly normalized following the start of Mg replacement, and brisk PTH response to hypocalcemic stimuli was obtained during the same test carried out a week after the Mg replacement. The data in this case thus suggest that: a) the acute regulation of PTH release by plasma ionized Ca is lost in the patient with hypomagnesemic hypocalcemia, and b) Mg deficiency itself is likely to be a primary cause of this disorder because the hormone response was clearly restored after shortterm Mg replacement alone.

Impaired parathyroid hormone response to hypocalcemic stimuli in a patient with hypomagnesemic hypocalcemia. Publishing Authors By Initials

Y Iwasaki,M Asai,M Yoshida,Y Oiso,K Hashimoto,

For similar abstracts research abstracts see: abstracts research

PUBMED ID PMID:

MEDLINE DATE:

Impaired parathyroid hormone response to hypocalcemic stimuli in a patient with hypomagnesemic hypocalcemia. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Journal of endocrinological investigation

VOLUME: 30

Page Numbers: 513-6

Journal Abbreviation: J. Endocrinol. Invest.

ISSN: 1720-8386

DAY: 24

MONTH: Jun

YEAR: 2007

Impaired parathyroid hormone response to hypocalcemic stimuli in a patient with hypomagnesemic hypocalcemia. Information

Number of References:

LANGUAGE: eng

NlmUniqueID: 7806594

Impaired parathyroid hormone response to hypocalcemic stimuli in a patient with hypomagnesemic hypocalcemia. Keywords Mesh Terms:

KEYWORDS:

MESH TERMS:

Chemical & Substance for Abstract: Impaired parathyroid hormone response to hypocalcemic stimuli in a patient with hypomagnesemic hypocalcemia. Information

Substance Name:

Registry Number:

Grant and Affiliation Information for Impaired parathyroid hormone response to hypocalcemic stimuli in a patient with hypomagnesemic hypocalcemia.

AFFILIATION: Department of Endocrinology, Metabolism, and Nephrology, Kochi Medical School, Kochi University, Kohasu, Oko-cho, Nankoku 783-8505, Japan. iwasaki@med.kochi-u.ac.jp

Country: Italy

AGENCY:

GRANT:

ACRONYM:

MEDLINETA: J Endocrinol Invest

REFSOURCE:

DATABASENAME:

ACCESSION NUMBER:

Number Hits: 0

Impaired parathyroid hormone response to hypocalcemic stimuli in a patient with hypomagnesemic hypocalcemia Related Publications

• 3,3-diphenylpentane skeleton as a steroid skeleton substitute: novel inhibitors of human 5alpha-reductase 1.
• A novel neuronal cell line derived from the ventrolateral region of the suprachiasmatic nucleus.
• A short, formal, biomimetic synthesis of (+/-)-polygalolides A and B.
• Airflow produced by dielectric barrier discharge between asymmetric parallel rod electrodes.
• Bone morphogenetic protein-2 modulates Wnt and frizzled expression and enhances the canonical pathway of Wnt signaling in normal keratinocytes.
• Breakdown of atheromatous plaque due to shear force from arterial perfusion cannula.
• CXCL16 is a novel mediator of the innate immunity of epidermal keratinocytes.
• Cellular distribution of Mr 25,000 protein, a protein partially overlapping phosvitin and lipovitellin 2 in vitellogenin B1, and yolk proteins in Xenopus laevis oocytes and embryos.
• Central type 2 corticotropin-releasing hormone receptor mediates hypothalamic-pituitary-adrenocortical axis activation in the rat.
• Close association of centrosomes to the distal ends of the microbody during its growth, division and partitioning in the green alga Klebsormidium flaccidum.
• Co-activation of the secondary somatosensory and auditory cortices facilitates frequency discrimination of vibrotactile stimuli.
• Deciphering the disease process of schizophrenia: the contribution of cortical gaba neurons.
• Edaravone inhibits collagen-induced arthritis possibly through suppression of nuclear factor-kappa B.
• Effects of Immunomodulatory Derivatives of Thalidomide (IMiDs) and Their Analogs on Cell-Differentiation, Cyclooxygenase Activity and Angiogenesis.
• Estrogenic activity in sediments contaminated by nonylphenol in Tokyo Bay (Japan) evaluated by vitellogenin induction in male mummichogs (Fundulus heteroclitus).
• Experiment of seed germination with low pressure environment simulator.
• Generation of different fates from multipotent muscle stem cells.
• High occupancy of sigma-1 receptors in the human brain after single oral administration of fluvoxamine: a positron emission tomography study using [11C]SA4503.
• Impaired parathyroid hormone response to hypocalcemic stimuli in a patient with hypomagnesemic hypocalcemia.
• Interleukin-6 has differential influence on the ability of adjuvant formulations to potentiate antibody responses to a Plasmodium falciparum blood-stage vaccine.
• Nanoscale metal coordination macrocycles fabricated by using "dimeric" dipyrrins.
• Phospholipase A(2)-mediated superoxide production of murine peritoneal macrophages induced by chrysotile stimulation.
• Plasma levels of DJ-1 as a possible marker for progression of sporadic Parkinson's disease.
• Plasmodium falciparum anti-MSP1-19 antibodies induced by MSP1-42 and MSP1-19 based vaccines differed in specificity and parasite growth inhibition in terms of recognition of conserved versus variant epitopes.
• Pleural dissemination of thymoma showing tumor regression after combined corticosteroid and tacrolimus therapy.
• Recurrent p.N767S mutation in the ATP2A2 gene in a Japanese family with haemorrhagic Darier disease clinically mimicking epidermolysis bullosa simplex with mottled pigmentation.
• The change of plasma endothelin-1 levels before and after surgery with or without Down syndrome.
• Two alloalleles of Xenopus laevis hairy2 gene-evolution of duplicated gene function from a developmental perspective.
• [Development of new drugs targeting glial cells]
• [Stem cell systems in skeletal muscle]