Impaired cortical inhibition in adult ADHD patients: a study with transcranial magnetic stimulation.

Impaired cortical inhibition in adult ADHD patients: a study with transcranial magnetic stimulation. Research Abstract Details 

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Impaired cortical inhibition in adult ADHD patients: a study with transcranial magnetic stimulation. Abstract Text:

M Schneider,W Retz,C Freitag,J Irsch,P Graf,P Retz-Junginger,M ,M Schneider,W Retz,C Freitag,J Irsch,P Graf,P Retz-Junginger,M ,

The aim of this study was to analyze motor inhibition and facilitation of adult ADHD patients using double pulse transcranial magnetic stimulation (TMS). Twenty-six right handed adult ADHD patients according to DSM-IV were investigated and compared to 26 age and sex-matched controls. In the left hemisphere, mean motor inhibition was 0.53 +/- 0.33 (mean +/- SD) in ADHD patients and 0.34 +/- 0.16 (mean +/- SD) in controls (p = 0.012). There were no significant differences in motor excitability concerning facilitation or in the right hemisphere. Decreased motor inhibition correlated with a higher symptom score derived from the Wender Reimherr Interview (WRI) (p = 0.28; p = 0.04) and also with self rated hyperactivity/impulsivity symptoms (p = 0.30; p = 0.03). In conclusion, decreased motor inhibition in adult ADHD corroborate similar findings in children with ADHD (Moll et al., 2000) and reflect disturbed impulsivity and hyperactivity on a neurophysiological level.

Impaired cortical inhibition in adult ADHD patients: a study with transcranial magnetic stimulation. Publishing Authors By Initials

M Schneider,W Retz,C Freitag,J Irsch,P Graf,P Retz-Junginger,M ,M Schneider,W Retz,C Freitag,J Irsch,P Graf,P Retz-Junginger,M ,

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Impaired cortical inhibition in adult ADHD patients: a study with transcranial magnetic stimulation. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Journal of neural transmission. Supplementum

VOLUME:

Page Numbers: 303-9

Journal Abbreviation: J. Neural Transm. Suppl.

ISSN: 0303-6995

DAY: 6

MONTH: 11

YEAR: 2007

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LANGUAGE: eng

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AFFILIATION: Institute for Forensic Psychology and Psychiatry, University of the Saarland, Homburg/Saar, Germany. marc.schneider@uniklinik-saarland.de

Country: Austria

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MEDLINETA: J Neural Transm Suppl

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