Impact of incidental magnetization transfer effects on inversion-recovery sequences that use a fast spin-echo readout.

Impact of incidental magnetization transfer effects on inversion-recovery sequences that use a fast spin-echo readout. Research Abstract Details 

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Impact of incidental magnetization transfer effects on inversion-recovery sequences that use a fast spin-echo readout. Abstract Text:

Simon J P Meara,Gareth J Barker,Simon J P Meara,Gareth J Barker,

Multislice MR images obtained using a fast spin-echo (FSE) readout are strongly affected by magnetization transfer (MT) effects, which will cause a decrease in the observed longitudinal relaxation times for tissues with a large bound water component. This is pertinent for FSE-based inversion-recovery (IR) sequences, as it would be expected to cause a change in the required inversion times. Furthermore, the effect will be greater as the number of slices that are acquired within the repetition time (TR) is increased. A pseudo-3D IR-FSE sequence was used to obtain images of a phantom consisting of thermally crosslinked bovine serum albumin. It was found that increasing the number of slabs acquired per TR period led to a decrease in the inversion time that maximally suppressed the signal from the MT phantom; this was not the case for water. This has important consequences for any IR imaging sequence that uses an FSE readout.

Impact of incidental magnetization transfer effects on inversion-recovery sequences that use a fast spin-echo readout. Publishing Authors By Initials

SJ Meara,GJ Barker,SJ Meara,GJ Barker,

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Impact of incidental magnetization transfer effects on inversion-recovery sequences that use a fast spin-echo readout. Journal Published:

PUBLICATION TYPE: Research Support, Non-U.S. Gov

Journal: Magnetic resonance in medicine : official journal

VOLUME: 58

Page Numbers: 825-9

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ISSN: 0740-3194

DAY: 2

MONTH: Oct

YEAR: 2007

Impact of incidental magnetization transfer effects on inversion-recovery sequences that use a fast spin-echo readout. Information

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LANGUAGE: eng

NlmUniqueID: 8505245

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Grant and Affiliation Information for Impact of incidental magnetization transfer effects on inversion-recovery sequences that use a fast spin-echo readout.

AFFILIATION: Imaging Science and Biomedical Engineering Research Group, University of Manchester, Manchester, United Kingdom. simon.meara@manchester.ac.uk

Country: United States

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MEDLINETA: Magn Reson Med

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