Impact of diabetes mellitus on treatment outcomes in patients with nasopharyngeal cancer.

Impact of diabetes mellitus on treatment outcomes in patients with nasopharyngeal cancer. Research Abstract Details 

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Impact of diabetes mellitus on treatment outcomes in patients with nasopharyngeal cancer. Abstract Text:

Hui Liu,Yunfei Xia,Nianji Cui,

Background and purpose: To determine the influence of diabetes mellitus on stages and long-term outcomes among patients with nasopharyngeal cancer. Material and methods: The study summarized 37 patients who were diagnosed as having diabetes mellitus and nasopharyngeal cancer and treated by radiotherapy between January 1999 and December 1999. With a median follow-up of 34.6 mo, we analyzed differences in RFS, MFS, DFS, and OS between the diabetes and the non-diabetes group. Results: 37 patients were involved in our study. According to the Chinese Fuzhou staging system for NPC, which was modified in 1992, 2 patients belong to stage I, 9 stage II, 17 stage III, and 6 stage IV. The 4-yr RFS of diabetes group and non-diabetes group was 52.1% vs 68.2%, the 4-yr MFS was 73.0% vs 72.0%, the 4-yr DFS was 35.1% vs 65.1%, and the OS was 67.6% vs 75.7%. The Wilcoxon (Gehan) test showed there was no significant difference between the two groups of RFS, MFS, and OS, while the diabetes group had a worse DFS than non-diabetes group (Wilcoxon p = 0.0047). Conclusions: Patients with diabetes had a worse DFS than non-diabetes, but statistic tests did not show significant differences in RFS, MFS, and OS; further studies should be continue to find out the results in the future.

Impact of diabetes mellitus on treatment outcomes in patients with nasopharyngeal cancer. Publishing Authors By Initials

H Liu,Y Xia,N Cui,

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Impact of diabetes mellitus on treatment outcomes in patients with nasopharyngeal cancer. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Medical oncology (Northwood, London, England)

VOLUME: 23

Page Numbers: 341-6

Journal Abbreviation: Med. Oncol.

ISSN: 1357-0560

DAY: 4

MONTH: 10

YEAR: 2006

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LANGUAGE: eng

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AFFILIATION: Department of Radiotherapy, The Affiliated Tumor Hospital of Sun-Yet-Sen University, Guangzhou, China.

Country: United States

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MEDLINETA: Med Oncol

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