Immunomodulatory effects of staphylococcal lipoteichoic acid in early Listeria monocytogenes infection in Balb/c-mice.

Immunomodulatory effects of staphylococcal lipoteichoic acid in early Listeria monocytogenes infection in Balb/c-mice. Research Abstract Details 

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Immunomodulatory effects of staphylococcal lipoteichoic acid in early Listeria monocytogenes infection in Balb/c-mice. Abstract Text:

Y Ohshima,J Beuth,H L Ko,K Roszkowski,D Hauck,G Pulverer,

Balb/c-mice were intravenously infected with 5 X 10(4) viable cells of Listeria monocytogenes SLCC 4013. Liver, lung and spleen of the animals showed heavy organ colonization 48 h after infection. Pretreatment of experimental animals with staphylococcal lipoteichoic acid (LTA; 2 mg i.p. 7 and 3 days before challenge) significantly reduced the bacterial count in these organs. In vitro, peritoneal macrophages from LTA-treated mice significantly reduced listerial viability as compared to control cells (p less than 0.0025). In vitro, exposure of macrophages from non-treated animals to LTA did not influence their bacterial killing ability.

Immunomodulatory effects of staphylococcal lipoteichoic acid in early Listeria monocytogenes infection in Balb/c-mice. Publishing Authors By Initials

Y Ohshima,J Beuth,HL Ko,K Roszkowski,D Hauck,G Pulverer,

For similar carbohydrates: glycosides: teichoic acids research abstracts see: carbohydrates: glycosides: teichoic acids research

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Immunomodulatory effects of staphylococcal lipoteichoic acid in early Listeria monocytogenes infection in Balb/c-mice. Journal Published:

PUBLICATION TYPE: Research Support, Non-U.S. Gov

Journal: Zentralblatt für Bakteriologie, Mikrobiologie, und

VOLUME: 269

Page Numbers: 251-6

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ISSN: 0176-6724

DAY: 12

MONTH: Aug

YEAR: 1988

Immunomodulatory effects of staphylococcal lipoteichoic acid in early Listeria monocytogenes infection in Balb/c-mice. Information

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LANGUAGE: eng

NlmUniqueID: 8403032

Immunomodulatory effects of staphylococcal lipoteichoic acid in early Listeria monocytogenes infection in Balb/c-mice. Keywords Mesh Terms:

KEYWORDS: Teichoic Acids

MESH TERMS: immunology

Chemical & Substance for Abstract: Immunomodulatory effects of staphylococcal lipoteichoic acid in early Listeria monocytogenes infection in Balb/c-mice. Information

Substance Name: lipoteichoic acid

Registry Number: 56411-57-5

Grant and Affiliation Information for Immunomodulatory effects of staphylococcal lipoteichoic acid in early Listeria monocytogenes infection in Balb/c-mice.

AFFILIATION: Hygiene-Institut, Universität zu Köln.

Country: GERMANY, WEST

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MEDLINETA: Zentralbl Bakteriol Mikrobiol

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