Immunologic abnormalities associated with primary anetoderma.

Immunologic abnormalities associated with primary anetoderma. Research Abstract Details 

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Immunologic abnormalities associated with primary anetoderma. Abstract Text:

BACKGROUND AND DESIGN--Primary anetoderma is a rare cutaneous elastolytic disorder, the etiopathogenesis of which has not yet been established. Six patients with primary anetoderma were studied in an attempt to assess the role of the immunologic system in the elastolytic process. The investigation included the medical history, physical examination, routine blood tests, specific tests for collagen diseases, prothrombin time, activated partial thromboplastin time, thyroxine, indirect immunofluorescence test, and skin biopsies for histopathologic study and direct immunofluorescence. RESULTS--Two of the patients presented with autoimmune disorders: the first had Graves' disease, lupus anticoagulant, and autoimmune hemolysis, and the second had systemic scleroderma. There were positive direct immunofluorescence findings in most of the patients. Furthermore, all of them were found to have serologic immunologic abnormalities, of which the most common was a positive antinuclear factor. CONCLUSIONS--These findings indicate that there is an immunologic involvement in primary anetoderma.

Immunologic abnormalities associated with primary anetoderma. Publishing Authors By Initials

For similar endocrine system: endocrine glands: thyroid gland research abstracts see: endocrine system: endocrine glands: thyroid gland research

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Immunologic abnormalities associated with primary anetoderma. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Archives of dermatology

VOLUME: 128

Page Numbers: 799-803

Journal Abbreviation: Arch Dermatol

ISSN: 0003-987X

DAY: 17

MONTH: Jun

YEAR: 1992

Immunologic abnormalities associated with primary anetoderma. Information

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LANGUAGE: eng

NlmUniqueID: 372433

Immunologic abnormalities associated with primary anetoderma. Keywords Mesh Terms:

KEYWORDS: Thyroid Gland

MESH TERMS: immunology

Chemical & Substance for Abstract: Immunologic abnormalities associated with primary anetoderma. Information

Substance Name: cold agglutinins

Registry Number: 0

Grant and Affiliation Information for Immunologic abnormalities associated with primary anetoderma.

AFFILIATION: Department of Dermatology, Beilinson Medical Center, Petah Tiqva, Israel.

Country: UNITED STATES

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MEDLINETA: Arch Dermatol

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