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Immunohistochemical localization of bone morphogenetic protein-2 in the oral and maxillofacial area of the human embryo.

Immunohistochemical localization of bone morphogenetic protein-2 in the oral and maxillofacial area of the human embryo. Research Abstract Details 

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  • Immunohistochemical localization of bone morphogenetic protein-2 in the oral and maxillofacial area of the human embryo. Abstract Text:

    t suzukiT Suzuki,k besshoK Bessho,n segamiN Segami,t iizukaT Iizuka,t nojimaT Nojima,

    The purpose of this study was to investigate the bone morphogenetic protein-2 (BMP-2) expression in oral and maxillofacial tissue of the human embryo. A human embryo was obtained from a patient with hysterorrhexis. The oral and maxillofacial area of the embryo was analyzed immunohistochemically using specific antibodies to BMP-2. BMP-2 was found mainly localized in developing teeth buds, jaw bone, striated and smooth muscle, spinal cord and nasal tracheal and oesophagal epithelium. However, it was not found in hair follicles. These findings are similar to those of BMP-2 and -4 gene expression in mouse and rat embryos. BMP-2 may be involved in the morphogenesis of oral and maxillofacial tissue in human embryos as well as those of other animals. These results will be of considerable benefit in the restoration and regeneration of the oral and maxillofacial tissue clinically.

    Immunohistochemical localization of bone morphogenetic protein-2 in the oral and maxillofacial area of the human embryo. Publishing Authors By Initials

    t suzukiT Suzuki,k besshoK Bessho,n segamiN Segami,t iizukaT Iizuka,t nojimaT Nojima,

    For similar peptides: intercellular signaling peptides and proteins: cytokines: transforming growth factor beta research abstracts see: peptides: intercellular signaling peptides and proteins: cytokines: transforming growth factor beta research

    PUBMED ID PMID:

    MEDLINE DATE:

    Immunohistochemical localization of bone morphogenetic protein-2 in the oral and maxillofacial area of the human embryo. Journal Published:

    PUBLICATION TYPE: Research Support, Non-U.S. Gov

    Journal: The British journal of oral & maxillofacial surger

    VOLUME: 39

    Page Numbers: 289-93

    Journal Abbreviation:

    ISSN: 0266-4356

    DAY: 19

    MONTH: Aug

    YEAR: 2001

    Immunohistochemical localization of bone morphogenetic protein-2 in the oral and maxillofacial area of the human embryo. Information

    Number of References:

    LANGUAGE: eng

    NlmUniqueID: 8405235

    Immunohistochemical localization of bone morphogenetic protein-2 in the oral and maxillofacial area of the human embryo. Keywords Mesh Terms:

    KEYWORDS: Transforming Growth Factor beta

    MESH TERMS: metabolism

    Chemical & Substance for Abstract: Immunohistochemical localization of bone morphogenetic protein-2 in the oral and maxillofacial area of the human embryo. Information

    Substance Name: bone morphogenetic protein 2

    Registry Number: 0

    Grant and Affiliation Information for Immunohistochemical localization of bone morphogenetic protein-2 in the oral and maxillofacial area of the human embryo.

    AFFILIATION: Department of Oral and Maxillofacial Surgery, Graduate School of Medicine, Kyoto University, Japan.

    Country: Scotland

    Scotland Research PublicationScotland Research Publication

    AGENCY:

    GRANT:

    ACRONYM:

    MEDLINETA: Br J Oral Maxillofac Surg

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    Number Hits: 0

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