Immunohistochemical distribution of phosphatidylglucoside using anti-phosphatidylglucoside monoclonal antibody (DIM21).

Immunohistochemical distribution of phosphatidylglucoside using anti-phosphatidylglucoside monoclonal antibody (DIM21). Research Abstract Details 

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Immunohistochemical distribution of phosphatidylglucoside using anti-phosphatidylglucoside monoclonal antibody (DIM21). Abstract Text:

Yukisato Kitamura,Toshiro Okazaki,Yasuko Nagatsuka,Yoshio Hirabayashi,Shinsuke Kato,Kazuhiko Hayashi,

The immunohistochemical distribution of phosphatidylglucoside (PhGlc) in organs obtained from human autopsy cases was investigated using the DIM21 antibody. Immunohistochemical staining was performed on formaline-fixed, paraffin-embedded sections using the simple stain peroxidase method. The sections were then subjected to antigen retrieval by microwave irradiation in citrate buffer. PhGlc expression was observed in not only the epithelial but also the non-epithelial components of several visceral organs. Squamous and glandular epithelial cells were positive for PhGlc in several organs. The surface areas of the epithelium, particularly the squamous epithelium, were positive. Mesothelial cells were also positive in some organs. Endothelial cells, polymorphonuclear (PMN) cells are positive in several organs. Macrophage is positive in many organs. Epithelial cells of the gallbladder were positive, however, the intrahepatic bile ducts were not positive. In the brain tissue, astroglial cells, the chorioide plexus, the pituitary gland, and ependymal cells were positive. Further investigation is indispensable in order to establish a relationship between cell differentiation and PhGlc expression.

Immunohistochemical distribution of phosphatidylglucoside using anti-phosphatidylglucoside monoclonal antibody (DIM21). Publishing Authors By Initials

Y Kitamura,T Okazaki,Y Nagatsuka,Y Hirabayashi,S Kato,K Hayashi,

For similar tissues: lymphoid tissue: thymus gland research abstracts see: tissues: lymphoid tissue: thymus gland research

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Immunohistochemical distribution of phosphatidylglucoside using anti-phosphatidylglucoside monoclonal antibody (DIM21). Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Biochemical and biophysical research communication

VOLUME: 362

Page Numbers: 252-5

Journal Abbreviation: Biochem. Biophys. Res. Commun.

ISSN: 0006-291X

DAY: 24

MONTH: 07

YEAR: 2007

Immunohistochemical distribution of phosphatidylglucoside using anti-phosphatidylglucoside monoclonal antibody (DIM21). Information

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LANGUAGE: eng

NlmUniqueID: 372516

Immunohistochemical distribution of phosphatidylglucoside using anti-phosphatidylglucoside monoclonal antibody (DIM21). Keywords Mesh Terms:

KEYWORDS: Thymus Gland

MESH TERMS: metabolism

Chemical & Substance for Abstract: Immunohistochemical distribution of phosphatidylglucoside using anti-phosphatidylglucoside monoclonal antibody (DIM21). Information

Substance Name: phosphatidylglucose

Registry Number: 0

Grant and Affiliation Information for Immunohistochemical distribution of phosphatidylglucoside using anti-phosphatidylglucoside monoclonal antibody (DIM21).

AFFILIATION: Department of Microbiology and Pathology, Field of Molecular Pathology, Faculty of Medicine, Tottori University, Nishi-chyou 86, Yonago 683-8503, Japan. nshyk@grape.med.tottori-u.ac.jp

Country: United States

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MEDLINETA: Biochem Biophys Res Commun

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