Immunohistochemical analysis of centromere protein F expression in buccal and gingival squamous cell carcinoma.

Immunohistochemical analysis of centromere protein F expression in buccal and gingival squamous cell carcinoma. Research Abstract Details 

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Immunohistochemical analysis of centromere protein F expression in buccal and gingival squamous cell carcinoma. Abstract Text:

Renelson L Esguerra,Lin Jia,Tomoatsu Kaneko,Kei Sakamoto,Norihiko Okada,Minoru Takagi,Renelson L Esguerra,Lin Jia,Tomoatsu Kaneko,Kei Sakamoto,Norihiko Okada,Minoru Takagi,

Centromere protein F (CENP-F) expression (localization and characteristics) in relation to tumor clinicopathological parameters was immunohistochemically examined and evaluated in 47 archival biopsy specimens of buccal and gingival squamous cell carcinomas (SCC). Centromere protein F expression was detected in 79% of the samples. An increase in the labeling index (LI) with WHO grading was obtained (P < 0.05). Correlations were obtained between the CENP-F LI and tumor size (P < 0.05). Immunoelectron microscopy showed CENP-F nuclear staining as punctate or fine dots. The present study shows that CENP-F expression and detection of a more specific cell subpopulation presents a theoretical advantage for the analysis of the precise cell cycle of G2 to M cells, compared to Ki-67.

Immunohistochemical analysis of centromere protein F expression in buccal and gingival squamous cell carcinoma. Publishing Authors By Initials

RL Esguerra,L Jia,T Kaneko,K Sakamoto,N Okada,M Takagi,RL Esguerra,L Jia,T Kaneko,K Sakamoto,N Okada,M Takagi,

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Immunohistochemical analysis of centromere protein F expression in buccal and gingival squamous cell carcinoma. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Pathology international

VOLUME: 54

Page Numbers: 82-9

Journal Abbreviation: Pathol. Int.

ISSN: 1320-5463

DAY: 14

MONTH: Feb

YEAR: 2004

Immunohistochemical analysis of centromere protein F expression in buccal and gingival squamous cell carcinoma. Information

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LANGUAGE: eng

NlmUniqueID: 9431380

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Grant and Affiliation Information for Immunohistochemical analysis of centromere protein F expression in buccal and gingival squamous cell carcinoma.

AFFILIATION: Molecular Pathology and Diagnostic Oral Pathology, Department of Oral Restitution, and Pulp Biology and Endodontics, Department of Restorative Sciences, Division of Oral Health Sciences, Graduate School, Tokyo Medical and Dental University, Tokyo, Japan.

Country: Australia

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MEDLINETA: Pathol Int

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