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Immunogenicity and safety of pneumococcal 7-valent conjugate vaccine (diphtheria CRM(197) protein conjugate; Prevenar ) in Korean infants: differences that are found in Asian children.

Immunogenicity and safety of pneumococcal 7-valent conjugate vaccine (diphtheria CRM(197) protein conjugate; Prevenar ) in Korean infants: differences that are found in Asian children. Research Abstract Details 

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  • Immunogenicity and safety of pneumococcal 7-valent conjugate vaccine (diphtheria CRM(197) protein conjugate; Prevenar ) in Korean infants: differences that are found in Asian children. Abstract Text:

    nam-hee kimNam-Hee Kim,jina leeJina Lee,sang jeong leeSang Jeong Lee,hyunju leeHyunju Lee,kyung-hyo kimKyung-Hyo Kim,su-eun parkSu-Eun Park,hoan-jong leeHoan-Jong Lee,nam-hee kimNam-Hee Kim,jina leeJina Lee,sang jeong leeSang Jeong Lee,hyunju leeHyunju Lee,kyung-hyo kimKyung-Hyo Kim,su-eun parkSu-Eun Park,hoan-jong leeHoan-Jong Lee,

    This study was conducted to determine the immunogenicity and safety of a 7-valent CRM197 protein conjugated pneumococcal vaccine (PCV7) in Korean infants immunized at 2, 4 and 6 months. A total of 202 infants were enrolled and 146 and 141 infants were, respectively, included in post-2nd dose and post-3rd dose immunogenicity evaluations conducted on a per protocol basis. After two and three PCV7 vaccinations, 63.0-98.0 and 97.2-100% of infants achieved an antibody level of >or=0.35microg/mL, respectively, with a lowest against serotype 6B. No vaccination-related serious adverse reactions were observed. Thus, PCV7 appears safe and highly immunogenic in Korean infants, and adopting two doses for a primary series could be a feasible option for facilitating vaccine coverage rate.

    Immunogenicity and safety of pneumococcal 7-valent conjugate vaccine (diphtheria CRM(197) protein conjugate; Prevenar ) in Korean infants: differences that are found in Asian children. Publishing Authors By Initials

    nh kimNH Kim,j leeJ Lee,sj leeSJ Lee,h leeH Lee,kh kimKH Kim,se parkSE Park,hj leeHJ Lee,nh kimNH Kim,j leeJ Lee,sj leeSJ Lee,h leeH Lee,kh kimKH Kim,se parkSE Park,hj leeHJ Lee,

    For similar abstracts research abstracts see: abstracts research

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    Immunogenicity and safety of pneumococcal 7-valent conjugate vaccine (diphtheria CRM(197) protein conjugate; Prevenar ) in Korean infants: differences that are found in Asian children. Journal Published:

    PUBLICATION TYPE: Research Support, Non-U.S. Gov

    Journal: Vaccine

    VOLUME: 25

    Page Numbers: 7858-65

    Journal Abbreviation: Vaccine

    ISSN: 0264-410X

    DAY: 31

    MONTH: 08

    YEAR: 2007

    Immunogenicity and safety of pneumococcal 7-valent conjugate vaccine (diphtheria CRM(197) protein conjugate; Prevenar ) in Korean infants: differences that are found in Asian children. Information

    Number of References:

    LANGUAGE: eng

    NlmUniqueID: 8406899

    Immunogenicity and safety of pneumococcal 7-valent conjugate vaccine (diphtheria CRM(197) protein conjugate; Prevenar ) in Korean infants: differences that are found in Asian children. Keywords Mesh Terms:

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    Grant and Affiliation Information for Immunogenicity and safety of pneumococcal 7-valent conjugate vaccine (diphtheria CRM(197) protein conjugate; Prevenar ) in Korean infants: differences that are found in Asian children.

    AFFILIATION: Department of Pediatrics, Seoul National University College of Medicine, Seoul, Republic of Korea.

    Country: Netherlands

    Netherlands Research PublicationNetherlands Research Publication

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    MEDLINETA: Vaccine

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    Immunogenicity and safety of pneumococcal 7-valent conjugate vaccine diphtheria CRM197 protein conjugate; Prevenar in Korean infants: differences that are found in Asian children Related Publications

     

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