Imaging Glucose-Regulated Insulin Secretion and Gene Expression in Single Islet beta-Cells: Control by AMP-Activated Protein Kinase.

Imaging Glucose-Regulated Insulin Secretion and Gene Expression in Single Islet beta-Cells: Control by AMP-Activated Protein Kinase. Research Abstract Details 

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Imaging Glucose-Regulated Insulin Secretion and Gene Expression in Single Islet beta-Cells: Control by AMP-Activated Protein Kinase. Abstract Text:

Guy A Rutter,Isabelle Leclerc,Takashi Tsuboi,Gabriela Da Silva Xavier, Diraison,Qingwen Qian,

The mechanisms by which changes in glucose concentration regulate gene expression and insulin secretion in pancreatic islet beta-cells are only partly understood. Here we describe the development of new technologies for examining these processes at the level of single living beta-cells. We also present recent findings, made using these and other techniques, which implicate a role for adenosine 5'-monophosphate-activated protein kinase in glucose signaling in these cells.

Imaging Glucose-Regulated Insulin Secretion and Gene Expression in Single Islet beta-Cells: Control by AMP-Activated Protein Kinase. Publishing Authors By Initials

GA Rutter,I Leclerc,T Tsuboi,Gda Xavier,F Diraison,Q Qian,

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Imaging Glucose-Regulated Insulin Secretion and Gene Expression in Single Islet beta-Cells: Control by AMP-Activated Protein Kinase. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Cell biochemistry and biophysics

VOLUME: 40

Page Numbers: 179-90

Journal Abbreviation: Cell Biochem. Biophys.

ISSN: 1085-9195

DAY: 3

MONTH: 08

YEAR: 2004

Imaging Glucose-Regulated Insulin Secretion and Gene Expression in Single Islet beta-Cells: Control by AMP-Activated Protein Kinase. Information

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LANGUAGE: eng

NlmUniqueID: 9701934

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Grant and Affiliation Information for Imaging Glucose-Regulated Insulin Secretion and Gene Expression in Single Islet beta-Cells: Control by AMP-Activated Protein Kinase.

AFFILIATION: Henry Wellcome Laboratories of Integrated Cell Signalling and Department of Biochemistry, School of Medical Sciences, University Walk, University of Bristol, United Kingdom.

Country: United States

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MEDLINETA: Cell Biochem Biophys

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