Imaging and examination strategies of normal male and female sex development and anatomy.

Imaging and examination strategies of normal male and female sex development and anatomy. Research Abstract Details 

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Imaging and examination strategies of normal male and female sex development and anatomy. Abstract Text:

Lutz ,Justine M Schober,

Over recent years a variety of new details on the developmental biology of sexual differentiation has been discovered. Moreover, important advances have been made in imaging and examination strategies for urogenital organs, and these have added new knowledge to our understanding of the 'normal' anatomy of the sexes. Both aspects contribute to the comprehension of phenotypic sex development, but they are not commonly presented in the same context. This will be attempted in this chapter, which aims to link discoveries in developmental biology to anatomical details shown by modern examination techniques. A review of the literature concerning the link between sexual development and imaging of urogenital organs was performed. Genes, proteins and pathways related to sexual differentiation were related to some organotypic features revealed by clinical examination techniques. Early 'organotypic' patterns can be identified in prostatic, urethral and genital development and followed into postnatal life. New imaging and endoscopy techniques allow for detailed descriptive anatomical studies, hopefully resulting in a broader understanding of sex development and a better genotype-phenotype correlation in defined disorders. Clinical description relying on imaging techniques should be related to knowledge of the genetic and endocrine factors influencing sex development in a specific and stepwise manner.

Imaging and examination strategies of normal male and female sex development and anatomy. Publishing Authors By Initials

L ,JM Schober,

For similar urogenital system research abstracts see: urogenital system research

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Imaging and examination strategies of normal male and female sex development and anatomy. Journal Published:

PUBLICATION TYPE: Review

Journal: Best practice & research. Clinical endocrinology &

VOLUME: 21

Page Numbers: 367-79

Journal Abbreviation: Best Pract. Res. Clin. Endocri

ISSN: 1521-690X

DAY: 30

MONTH: Sep

YEAR: 2007

Imaging and examination strategies of normal male and female sex development and anatomy. Information

Number of References: 39

LANGUAGE: eng

NlmUniqueID: 101120682

Imaging and examination strategies of normal male and female sex development and anatomy. Keywords Mesh Terms:

KEYWORDS: Urogenital System

MESH TERMS: growth & development

Chemical & Substance for Abstract: Imaging and examination strategies of normal male and female sex development and anatomy. Information

Substance Name: Genetic Markers

Registry Number: 0

Grant and Affiliation Information for Imaging and examination strategies of normal male and female sex development and anatomy.

AFFILIATION: Department of Paediatric Surgery, University of Lübeck, Ratzeburger Allee 160, 23538 Lübeck, Germany. wuensch@medinf.mu-luebeck.de

Country: England

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MEDLINETA: Best Pract Res Clin Endocrinol

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