Ikaros and chromatin regulation in early hematopoiesis.

Ikaros and chromatin regulation in early hematopoiesis. Research Abstract Details 

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Ikaros and chromatin regulation in early hematopoiesis. Abstract Text:

Samuel Yao-Ming Ng,Toshimi Yoshida,Katia Georgopoulos,

Hematopoiesis is the developmental process by which all blood and immune cells are generated. A decade-old scheme has supported an early and complete separation of the erythro-myeloid from the lymphoid lineages. Recent advances have re-drawn this map, separating lymphoid and myeloid from erythroid programs early in development. Subsequently, the fate restriction of both the lympho-myeloid and the erythro-megakaryocyte progenitors is dependent on Ikaros and its associated chromatin regulators. Genetic studies of this family of nuclear factors are now providing unique insight into the functional molecular signatures that bestow plasticity to the hematopoietic stem cell and its early progeny.

Ikaros and chromatin regulation in early hematopoiesis. Publishing Authors By Initials

SY Ng,T Yoshida,K Georgopoulos,

For similar cells: stem cells: multipotent stem cells research abstracts see: cells: stem cells: multipotent stem cells research

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Ikaros and chromatin regulation in early hematopoiesis. Journal Published:

PUBLICATION TYPE: Review

Journal: Current opinion in immunology

VOLUME: 19

Page Numbers: 116-22

Journal Abbreviation: Curr. Opin. Immunol.

ISSN: 0952-7915

DAY: 20

MONTH: 02

YEAR: 2007

Ikaros and chromatin regulation in early hematopoiesis. Information

Number of References: 29

LANGUAGE: eng

NlmUniqueID: 8900118

Ikaros and chromatin regulation in early hematopoiesis. Keywords Mesh Terms:

KEYWORDS: Multipotent Stem Cells

MESH TERMS: metabolism

Chemical & Substance for Abstract: Ikaros and chromatin regulation in early hematopoiesis. Information

Substance Name: Ikaros Transcription Factor

Registry Number: 148971-36-2

Grant and Affiliation Information for Ikaros and chromatin regulation in early hematopoiesis.

AFFILIATION: Cutaneous Biology Research Center, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA 02129, USA.

Country: England

AGENCY: United States NIAID

GRANT: 5T32 AI07529

ACRONYM: AI

MEDLINETA: Curr Opin Immunol

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