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Idiopathic interstitial pneumonias: progress in classification, diagnosis, pathogenesis and management.

Idiopathic interstitial pneumonias: progress in classification, diagnosis, pathogenesis and management. Research Abstract Details 

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  • Idiopathic interstitial pneumonias: progress in classification, diagnosis, pathogenesis and management. Abstract Text:

    talmadge e kingTalmadge E King,

    The idiopathic interstitial pneumonias are a heterogeneous group of poorly understood diseases with often devastating consequences for those afflicted. Subclassification of the idiopathic interstitial pneumonia based on clinical-radiological-pathological criteria has highlighted important pathogenic, therapeutic and prognostic implications. The most critical distinction is the presence of usual interstitial pneumonia, the histopathological pattern seen in idiopathic pulmonary fibrosis. Idiopathic pulmonary fibrosis has a worse response to therapy and prognosis. New insight into the pathophysiology of usual interstitial pneumonia suggests a distinctly fibroproliferative process, and antifibrotic therapies show promise. While the clinical and radiographic diagnosis of idiopathic interstitial pneumonias can be made confidently in some cases, many patients require surgical lung biopsy to determine their underlying histopathology. A structured, clinical-radiological-pathological approach to the diagnosis of the idiopathic interstitial pneumonias, with particular attention to the identification of idiopathic pulmonary fibrosis, insures proper therapy, enhances prognostication, and allows for further investigation of therapies aimed at distinct pathophysiology.

    Idiopathic interstitial pneumonias: progress in classification, diagnosis, pathogenesis and management. Publishing Authors By Initials

    te kingTE King,

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    Idiopathic interstitial pneumonias: progress in classification, diagnosis, pathogenesis and management. Journal Published:

    PUBLICATION TYPE: Journal Article

    Journal: Transactions of the American Clinical and Climatol

    VOLUME: 115

    Page Numbers: 43-78

    Journal Abbreviation: Trans. Am. Clin. Climatol. Ass

    ISSN: 0065-7778

    DAY: 24

    MONTH: 10

    YEAR: 2004

    Idiopathic interstitial pneumonias: progress in classification, diagnosis, pathogenesis and management. Information

    Number of References:

    LANGUAGE: eng

    NlmUniqueID: 7507559

    Idiopathic interstitial pneumonias: progress in classification, diagnosis, pathogenesis and management. Keywords Mesh Terms:

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    Grant and Affiliation Information for Idiopathic interstitial pneumonias: progress in classification, diagnosis, pathogenesis and management.

    AFFILIATION: San Francisco, California.

    Country: United States

    United States Research PublicationUnited States Research Publication

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    MEDLINETA: Trans Am Clin Climatol Assoc

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