Identification of Leishmania donovani as a cause of cutaneous leishmaniasis in Sudan.

Identification of Leishmania donovani as a cause of cutaneous leishmaniasis in Sudan. Research Abstract Details 

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Identification of Leishmania donovani as a cause of cutaneous leishmaniasis in Sudan. Abstract Text:

E M Elamin,I Guizani,S Guerbouj,M Gramiccia,A M El Hassan,T Di Muccio,M A Taha,M M Mukhtar,E M Elamin,I Guizani,S Guerbouj,M Gramiccia,A M El Hassan,T Di Muccio,M A Taha,M M Mukhtar,

Eight patients with cutaneous ulcers were referred to the Institute of Endemic Diseases, Khartoum, Sudan, from June 2000 to March 2002 for the diagnosis of suspected cutaneous leishmaniasis (CL). Diagnosis was confirmed parasitologically by both positive Giemsa-stained smears and successful culture of Leishmania promastigotes in NNN medium. The eight parasite isolates were shown to belong to the Leishmania donovani complex by kDNA PCR. Isoenzyme typing of three isolates revealed that they were identical to the L. donovani MON-82 reference strain, and the gp63 PCR-RFLP profile showed similar patterns to a reference strain of MON-82. CL is endemic in most regions of Sudan and has been reported previously as being caused by L. major MON-74. The results of this study suggest that L. donovani is also a cause of CL in Sudan and that further study of isolates from Sudanese patients with cutaneous ulcers is warranted to ascertain whether L. donovani or L. major is the causative agent.

Identification of Leishmania donovani as a cause of cutaneous leishmaniasis in Sudan. Publishing Authors By Initials

EM Elamin,I Guizani,S Guerbouj,M Gramiccia,AM El Hassan,T Di Muccio,MA Taha,MM Mukhtar,EM Elamin,I Guizani,S Guerbouj,M Gramiccia,AM El Hassan,T Di Muccio,MA Taha,MM Mukhtar,

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Identification of Leishmania donovani as a cause of cutaneous leishmaniasis in Sudan. Journal Published:

PUBLICATION TYPE: Research Support, Non-U.S. Gov

Journal: Transactions of the Royal Society of Tropical Medi

VOLUME: 102

Page Numbers: 54-7

Journal Abbreviation: Trans. R. Soc. Trop. Med. Hyg.

ISSN: 0035-9203

DAY: 26

MONTH: 11

YEAR: 2007

Identification of Leishmania donovani as a cause of cutaneous leishmaniasis in Sudan. Information

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LANGUAGE: eng

NlmUniqueID: 7506129

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Grant and Affiliation Information for Identification of Leishmania donovani as a cause of cutaneous leishmaniasis in Sudan.

AFFILIATION: Institute of Endemic Diseases, University of Khartoum, Khartoum, Sudan.

Country: England

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MEDLINETA: Trans R Soc Trop Med Hyg

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