Identification of glucosyl sphingosine from Gaucher's spleen by gas chromatography-electron impact and GC-chemical ionization mass spectrometry.

Identification of glucosyl sphingosine from Gaucher's spleen by gas chromatography-electron impact and GC-chemical ionization mass spectrometry. Research Abstract Details 

Research Abstract Table of Contents

Jump to the:

Identification of glucosyl sphingosine from Gaucher's spleen by gas chromatography-electron impact and GC-chemical ionization mass spectrometry. Abstract Text:

M Oshima,

Glucosyl sphingosine was isolated from the spleen of a patient with adult-type Gaucher's disease. The yield of purified glucosyl sphingosine was 9.3 nmoles/g wet tissue. The gas chromatography-chemical ionization mass spectrum of acetylated glucosyl sphingosine showed peaks due to the presence of ions formed by successive loss of acetic acid (mass 60) from the molecular ion (QM+, 714). Fragments from acetylated sugar, m/e 331, and from the sphingosine residue, m/e 306, were also detected. The GC-CI mass spectrum of the trimethylsilyl derivative of glucosyl sphingosine showed peaks due to the molecular ion (QM+, 822), ions from the sugar moiety (m/e 361, 271), and ions from the sphingosine base (m/e 264, 280). Fragmentation analysis of the purified sample by GC-EI and GC-CI mass spectrometry confirmed the structure glucopyranosyl(1 leads to 1)-1,3-dihydroxy-2-amino-4-octadecene.

Identification of glucosyl sphingosine from Gaucher's spleen by gas chromatography-electron impact and GC-chemical ionization mass spectrometry. Publishing Authors By Initials

M Oshima,

For similar tissues: lymphoid tissue: spleen research abstracts see: tissues: lymphoid tissue: spleen research

PUBMED ID PMID:

MEDLINE DATE:

Identification of glucosyl sphingosine from Gaucher's spleen by gas chromatography-electron impact and GC-chemical ionization mass spectrometry. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Journal of biochemistry

VOLUME: 80

Page Numbers: 53-9

Journal Abbreviation: J. Biochem.

ISSN: 0021-924X

DAY: 19

MONTH: Jul

YEAR: 1976

Identification of glucosyl sphingosine from Gaucher's spleen by gas chromatography-electron impact and GC-chemical ionization mass spectrometry. Information

Number of References:

LANGUAGE: eng

NlmUniqueID: 376600

Identification of glucosyl sphingosine from Gaucher's spleen by gas chromatography-electron impact and GC-chemical ionization mass spectrometry. Keywords Mesh Terms:

KEYWORDS: Spleen

MESH TERMS: metabolism

Chemical & Substance for Abstract: Identification of glucosyl sphingosine from Gaucher's spleen by gas chromatography-electron impact and GC-chemical ionization mass spectrometry. Information

Substance Name: Sphingosine

Registry Number: 123-78-4

Grant and Affiliation Information for Identification of glucosyl sphingosine from Gaucher's spleen by gas chromatography-electron impact and GC-chemical ionization mass spectrometry.

AFFILIATION:

Country: JAPAN

AGENCY:

GRANT:

ACRONYM:

MEDLINETA: J Biochem

REFSOURCE:

DATABASENAME:

ACCESSION NUMBER:

Number Hits: 0

Identification of glucosyl sphingosine from Gaucher's spleen by gas chromatography-electron impact and GC-chemical ionization mass spectrometry Related Publications

• Antiferromagnetic Ordering Driven by the Molecular Orbital Order of C60 in alpha;{'}-Tetra-Kis-(Dimethylamino)-Ethylene-C60.
• Bacteriophage phiNS11: a lipid-containing phage of acidophilic thermophilic bacteria. II. Purification and some properties of the phage.
• Bacteriophage phiNS11: a lipid-containing phage of acidophilic thermophilic bacteria. III. Characterization of viral components.
• C-type cytochromes isloated from an extreme thermophile, Thermus thermophilus HB8.
• Cancer survival trends in Osaka, Japan: the influence of age and stage at diagnosis.
• Changing expression of ABH blood group and cryptic T-antigens of noninvasive and superficially invasive papillary transitional cell carcinoma of the bladder from initial occurrence to malignant progression.
• Distinctive change in male liver cancer incidence rate between the 1970s and 1990s in Japan: comparison with Japanese-Americans and US whites.
• Effective structure of a leader open reading frame for enhancing the expression of GC-rich genes.
• Ets2 is required for trophoblast stem cell self-renewal.
• Hospital procedure volume and survival of cancer patients in Osaka, Japan: a population-based study with latest cases.
• Identification of glucosyl sphingosine from Gaucher's spleen by gas chromatography-electron impact and GC-chemical ionization mass spectrometry.
• Isolation and characterization of virulent yellowtail ascites virus.
• Kinetic studies on redox reactions of hemoproteins. II. Reduction of thermoresistant cytochrome c-552 and horse heart cytochrome c by ascorbic acid.
• Microwave-assisted palladium-catalyzed direct arylation of 1,4-disubstituted 1,2,3-triazoles with aryl chlorides.
• Nickel-catalyzed beta-boration of alpha,beta-unsaturated esters and amides with bis(pinacolato)diboron.
• Non-contact three-dimensional mapping and ablation of swallowing-induced atrial tachyarrhythmias: two case reports.
• Phenomics and lamins: from disease to therapy.
• Polypeptide synthesis directed by DNA as a messenger in cell-free polypeptide synthesis by extreme thermophiles, Thermus thermophilus HB27 and Sulfolobus tokodaii strain 7.
• Purification and characterization of arylamidase from monkey brain.
• Purification and properties of oxytocinase (cystine amino-peptidase) from monkey placenta.
• Purification and some properties of cytochrome c-552 from an extreme thermophile, Thermus thermophilus HB8.
• SOD2 polymorphisms: unmasking the effect of polymorphism on splicing.
• Synthesis of (arylalkenyl)silanes by palladium-catalyzed regiospecific and stereoselective allyl transfer from silyl-substituted homoallyl alcohols to aryl halides.
• Synthesis of Benzo[b]thiophenes by Cyclization of Arylketene Dithioacetal Monoxides under Pummerer-like Conditions.
• Synthesis of various phosphodiesters and phosphomonoesters with ribonuclease N.
• Unique polyamines produced by an extreme thermophile, Thermus thermophilus.
• [Considerations for home environment of patients with dementia]
• [Effects of skill level on individual behavioral counseling for smoking cessation]
• [Relations of clinicopathological findings to expression of ABH blood group and Thomsen-Friedenrich antigens in initially superficial papillary transitional cell carcinomas of the bladder developing subsequent malignant progression]
• [Vitamin K2 as a potential therapeutic agent for glucocorticoid-induced osteoporosis]