Identification of a novel C-type lectin gene in Japanese flounder, Paralichthys olivaceus.

Identification of a novel C-type lectin gene in Japanese flounder, Paralichthys olivaceus. Research Abstract Details 

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Identification of a novel C-type lectin gene in Japanese flounder, Paralichthys olivaceus. Abstract Text:

Hidehiro Kondo,Andrew Gung Yeu Tzeh,Ikuo Hirono,Takashi Aoki,

A novel C-type lectin of Japanese flounder (JFCTL) was identified among Japanese flounder liver EST. Of 2083 of Japanese flounder liver ESTs in the GenBank database, 48 were identical to JFCTL, suggesting that JFCTL is abundantly produced in liver. JFCTL cDNA contains an open reading frame of 642 bp encoding 214 amino acids. A C-type lectin domain was conserved in the deduced amino acid sequence. The protein showed homology to transmembrane-type C-type lectin receptors rather than the soluble C-type lectin so far reported, but it was predicted to be a secreted protein. Transcription of JFCTL was restricted to the liver. Although the mRNA was not induced after the treatment of fish with formalin-killed Edwardsiella tarda, expression was higher at 20 degrees C than at 10 degrees C.

Identification of a novel C-type lectin gene in Japanese flounder, Paralichthys olivaceus. Publishing Authors By Initials

H Kondo,AG Yeu Tzeh,I Hirono,T Aoki,

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Identification of a novel C-type lectin gene in Japanese flounder, Paralichthys olivaceus. Journal Published:

PUBLICATION TYPE: Research Support, Non-U.S. Gov

Journal: Fish & shellfish immunology

VOLUME: 23

Page Numbers: 1089-94

Journal Abbreviation: Fish Shellfish Immunol.

ISSN: 1050-4648

DAY: 18

MONTH: 05

YEAR: 2007

Identification of a novel C-type lectin gene in Japanese flounder, Paralichthys olivaceus. Information

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LANGUAGE: eng

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Grant and Affiliation Information for Identification of a novel C-type lectin gene in Japanese flounder, Paralichthys olivaceus.

AFFILIATION: Laboratory of Genome Science, Tokyo University of Marine Science and Technology, Konan 4-5-7, Minato, Tokyo 108-8477, Japan.

Country: England

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MEDLINETA: Fish Shellfish Immunol

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