Identification, characterization and manipulation of Babesia-bovis-infected red blood cells using microfluidics technology.

Identification, characterization and manipulation of Babesia-bovis-infected red blood cells using microfluidics technology. Research Abstract Details 

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Identification, characterization and manipulation of Babesia-bovis-infected red blood cells using microfluidics technology. Abstract Text:

E Nascimento,T Silva,A Oliva,

Nowadays numerous microfluidic systems are being developed to address a variety of clinical problems. Latest advances in microfluidic technology are promising to revolutionize the detection of pathogens in vivo through the development of integrated lab-on-chip devices. Such microfabricated systems will undertake all steps in sample analysis from collection and preparation to molecular detection. Micro total analysis systems are suitable candidates for point of care diagnostics due to small size, low cost production and enabled portability. The work here presented aimed the use of microfluidic platforms to identify and manipulate bovine red blood cells infected by the protozoan parasite Babesia bovis. A microfabricated device based on impedance spectroscopy was used for single cell discrimination and its sensitivity and applicability as a diagnostic method for bovine babesiosis was studied. Furthermore, manipulation and sorting of normal and infected red blood cells was performed on a dielectrophoresis based microfabricated cell cytometer. Single cell analysis of normal and B. bovis infected red blood cells was performed by electrorotation and dielectric parameters such as permittivities and conductivities of the cellular membrane and cytoplasm were determined.

Identification, characterization and manipulation of Babesia-bovis-infected red blood cells using microfluidics technology. Publishing Authors By Initials

E Nascimento,T Silva,A Oliva,

For similar biological sciences: biology: parasitology research abstracts see: biological sciences: biology: parasitology research

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Identification, characterization and manipulation of Babesia-bovis-infected red blood cells using microfluidics technology. Journal Published:

PUBLICATION TYPE: Research Support, Non-U.S. Gov

Journal: Parassitologia

VOLUME: 49 Suppl 1

Page Numbers: 45-52

Journal Abbreviation: Parassitologia

ISSN: 0048-2951

DAY: 29

MONTH: May

YEAR: 2007

Identification, characterization and manipulation of Babesia-bovis-infected red blood cells using microfluidics technology. Information

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LANGUAGE: eng

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Identification, characterization and manipulation of Babesia-bovis-infected red blood cells using microfluidics technology. Keywords Mesh Terms:

KEYWORDS: Parasitology

MESH TERMS: methods

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Grant and Affiliation Information for Identification, characterization and manipulation of Babesia-bovis-infected red blood cells using microfluidics technology.

AFFILIATION: Biosensors/Biomolecular Diagnostics Laboratory, Oeiras/Portugal.

Country: Italy

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MEDLINETA: Parassitologia

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