Identification and functional expression of HCx31.9, a novel gap junction gene.

Identification and functional expression of HCx31.9, a novel gap junction gene. Research Abstract Details 

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Identification and functional expression of HCx31.9, a novel gap junction gene. Abstract Text:

N Belluardo,T W White,M Srinivas,A Trovato-Salinaro,H Ripps,G ,R Bruzzone,D F Condorelli,

By combining in silico and bench molecular biology methods we have identified a novel human gap junction gene that encodes a protein designated HCx31.9. We have determined its human chromosomal location and gene structure, and we have identified a putative mouse ortholog, mCx30.2. We have observed the presence of HCx31.9 in human cerebral cortex, liver, heart, spleen, lung, and kidney and the presence of mCx30.2 in mouse cerebral cortex, liver and lung. Moreover, preliminary data on the electrophysiological properties of HCx31.9 have been obtained by functional expression in paired Xenopus oocytes and in transfected N2A cells.

Identification and functional expression of HCx31.9, a novel gap junction gene. Publishing Authors By Initials

N Belluardo,TW White,M Srinivas,A Trovato-Salinaro,H Ripps,G ,R Bruzzone,DF Condorelli,

For similar animals: chordata: vertebrates: amphibia: anura: pipidae: xenopus: xenopus laevis research abstracts see: animals: chordata: vertebrates: amphibia: anura: pipidae: xenopus: xenopus laevis research

PUBMED ID PMID:

MEDLINE DATE:

Identification and functional expression of HCx31.9, a novel gap junction gene. Journal Published:

PUBLICATION TYPE: Research Support, U.S. Gov't,

Journal: Cell communication & adhesion

VOLUME: 8

Page Numbers: 173-8

Journal Abbreviation: Cell Commun. Adhes.

ISSN: 1541-9061

DAY: 8

MONTH: 12

YEAR: 2001

Identification and functional expression of HCx31.9, a novel gap junction gene. Information

Number of References:

LANGUAGE: eng

NlmUniqueID: 101096596

Identification and functional expression of HCx31.9, a novel gap junction gene. Keywords Mesh Terms:

KEYWORDS: Xenopus laevis

MESH TERMS: physiology

Chemical & Substance for Abstract: Identification and functional expression of HCx31.9, a novel gap junction gene. Information

Substance Name: GJD3 protein, human

Registry Number: 0

Grant and Affiliation Information for Identification and functional expression of HCx31.9, a novel gap junction gene.

AFFILIATION: Department of Experimental Medicine, University of Palermo, Italy.

Country: Switzerland

AGENCY: United States NEI

GRANT: EY-13163

ACRONYM: EY

MEDLINETA: Cell Commun Adhes

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