Identification and characterization of extragenic suppressors of the yeast sec12 ts mutation.

Identification and characterization of extragenic suppressors of the yeast sec12 ts mutation. Research Abstract Details 

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Identification and characterization of extragenic suppressors of the yeast sec12 ts mutation. Abstract Text:

A Nakano,

The product of the yeast SEC12 gene is the most upstream player as far as we know in the events of vesicle budding from the endoplasmic reticulum membrane. To understand how the Sec12p function could be regulated, I identified three extragenic suppressor mutations of the sec12 ts mutation. RST1DS is a dominant mutation and causes elevated expression of Sec12p. rst2 and rst3 are recessive and give pleiotropic phenotypes including slow growth at low temperatures and heterogeneous modification of Sec12p. Their possible roles are discussed.

Identification and characterization of extragenic suppressors of the yeast sec12 ts mutation. Publishing Authors By Initials

A Nakano,

For similar genetic processes: mutagenesis: suppression, genetic research abstracts see: genetic processes: mutagenesis: suppression, genetic research

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Identification and characterization of extragenic suppressors of the yeast sec12 ts mutation. Journal Published:

PUBLICATION TYPE: Research Support, Non-U.S. Gov

Journal: Journal of biochemistry

VOLUME: 120

Page Numbers: 642-6

Journal Abbreviation: J. Biochem.

ISSN: 0021-924X

DAY: 19

MONTH: Sep

YEAR: 1996

Identification and characterization of extragenic suppressors of the yeast sec12 ts mutation. Information

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LANGUAGE: eng

NlmUniqueID: 376600

Identification and characterization of extragenic suppressors of the yeast sec12 ts mutation. Keywords Mesh Terms:

KEYWORDS: Suppression, Genetic

MESH TERMS: metabolism

Chemical & Substance for Abstract: Identification and characterization of extragenic suppressors of the yeast sec12 ts mutation. Information

Substance Name: Saccharomyces cerevisiae Proteins

Registry Number: 0

Grant and Affiliation Information for Identification and characterization of extragenic suppressors of the yeast sec12 ts mutation.

AFFILIATION: Department of Biological Sciences, Graduate School of Science, University of Tokyo. nakano@uts2.s.u.-tokyo.ac.jp

Country: JAPAN

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MEDLINETA: J Biochem

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