Identification and characterization of a novel calcineurin-binding protein in scallop testis.

Identification and characterization of a novel calcineurin-binding protein in scallop testis. Research Abstract Details 

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Identification and characterization of a novel calcineurin-binding protein in scallop testis. Abstract Text:

Akiko Nakatomi,Michio Yazawa,

Calcineurin has been inferred to function in meiosis and spermiogenesis in testis. Here, we identified a calcineurin-binding protein in scallop testis by Far-Western blot analysis using purified calcineurin as a probe. The molecular mass of the binding protein estimated on the blot was 75 kDa. The isolated cDNA clone encoded a novel 474-residue protein, named CaNBP75. The region between T6 and A210 of CaNBP75 was responsible for the interaction with calcineurin. CaNBP75 was predominantly expressed in testis and ovary of scallop. Thus, CaNBP75 may modulate the physiological function of calcineurin in the testis and ovary of scallop, such as in spermiogenesis or meiosis.

Identification and characterization of a novel calcineurin-binding protein in scallop testis. Publishing Authors By Initials

A Nakatomi,M Yazawa,

For similar urogenital system: genitalia: genitalia, male: testis research abstracts see: urogenital system: genitalia: genitalia, male: testis research

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Identification and characterization of a novel calcineurin-binding protein in scallop testis. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Journal of biochemistry

VOLUME: 133

Page Numbers: 159-64

Journal Abbreviation: J. Biochem.

ISSN: 0021-924X

DAY: 19

MONTH: Feb

YEAR: 2003

Identification and characterization of a novel calcineurin-binding protein in scallop testis. Information

Number of References:

LANGUAGE: eng

NlmUniqueID: 376600

Identification and characterization of a novel calcineurin-binding protein in scallop testis. Keywords Mesh Terms:

KEYWORDS: Testis

MESH TERMS: chemistry

Chemical & Substance for Abstract: Identification and characterization of a novel calcineurin-binding protein in scallop testis. Information

Substance Name: Calcineurin

Registry Number: EC 3.1.3.-

Grant and Affiliation Information for Identification and characterization of a novel calcineurin-binding protein in scallop testis.

AFFILIATION: Division of Chemistry, Graduate School of Science, Hokkaido University, Sapporo 060-0810, Japan.

Country: Japan

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MEDLINETA: J Biochem

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ACCESSION NUMBER: AB099485

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