Hypothermia for the management of intracranial hypertension in acute liver failure.

Hypothermia for the management of intracranial hypertension in acute liver failure. Research Abstract Details 

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Hypothermia for the management of intracranial hypertension in acute liver failure. Abstract Text:

Rajiv Jalan,Nathan A Davies,Steven W M Olde Damink,

Increased intracranial pressure in patients with acute liver failure (ALF) remains a major immediate cause of mortality. Several studies in animal models of ALF set the stage for the clinical application of moderate hypothermia in man. Studies in patients with ALF and increased intracranial hypertension have shown that temperatures as low as 32 degrees C are safe and effectively reduce increased intracranial pressure unresponsive to other medical therapies, and can be used as a successful bridge to liver transplantation. Data from studies in patients undergoing liver transplantation for ALF suggest that increases in intracranial pressure can be prevented during the dissection and reperfusion phases of the operation if the patients are maintained hypothermic during surgery. The present review focuses upon the clinical aspects of using hypothermia as a treatment of increased intracranial pressure in patients with ALF.

Hypothermia for the management of intracranial hypertension in acute liver failure. Publishing Authors By Initials

R Jalan,NA Davies,SW Olde Damink,

For similar surgical procedures, operative: digestive system surgical procedures: liver transplantation research abstracts see: surgical procedures, operative: digestive system surgical procedures: liver transplantation research

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Hypothermia for the management of intracranial hypertension in acute liver failure. Journal Published:

PUBLICATION TYPE: Review

Journal: Metabolic brain disease

VOLUME: 17

Page Numbers: 437-44

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ISSN: 0885-7490

DAY: 14

MONTH: Dec

YEAR: 2002

Hypothermia for the management of intracranial hypertension in acute liver failure. Information

Number of References: 20

LANGUAGE: eng

NlmUniqueID: 8610370

Hypothermia for the management of intracranial hypertension in acute liver failure. Keywords Mesh Terms:

KEYWORDS: Liver Transplantation

MESH TERMS: complications

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Grant and Affiliation Information for Hypothermia for the management of intracranial hypertension in acute liver failure.

AFFILIATION: Institute of Hepatology, University College London Medical School and Hospital, London, United Kingdom. r.jalan@ucl.ac.uk

Country: United States

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MEDLINETA: Metab Brain Dis

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