Hypothalamic-pituitary-adrenal axis dysregulation among diabetic outpatients.

Hypothalamic-pituitary-adrenal axis dysregulation among diabetic outpatients. Research Abstract Details 

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Hypothalamic-pituitary-adrenal axis dysregulation among diabetic outpatients. Abstract Text:

We compared insulin-requiring diabetic outpatients (n = 49) with normal controls (n = 42) for indices of hypothalamic-pituitary-adrenal (HPA) axis activity. Diabetic patients showed significantly elevated 9 a.m. plasma levels of cortisol as well as significantly elevated plasma levels of cortisol and adrenocorticotropic hormone (ACTH) at both 4 p.m. before and 4 p.m. after dexamethasone. Also, there was a significant correlation between postdexamethasone plasma levels of ACTH and duration of diabetes. These results suggest that HPA-axis dysregulation is found among diabetic outpatients. The possible psychiatric implications are discussed.

Hypothalamic-pituitary-adrenal axis dysregulation among diabetic outpatients. Publishing Authors By Initials

For similar endocrine system: endocrine glands: pituitary-adrenal system research abstracts see: endocrine system: endocrine glands: pituitary-adrenal system research

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Hypothalamic-pituitary-adrenal axis dysregulation among diabetic outpatients. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Psychiatry research

VOLUME: 31

Page Numbers: 31-7

Journal Abbreviation: Psychiatry Res

ISSN: 0165-1781

DAY: 17

MONTH: Jan

YEAR: 1990

Hypothalamic-pituitary-adrenal axis dysregulation among diabetic outpatients. Information

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LANGUAGE: eng

NlmUniqueID: 7911385

Hypothalamic-pituitary-adrenal axis dysregulation among diabetic outpatients. Keywords Mesh Terms:

KEYWORDS: Pituitary-Adrenal System

MESH TERMS: physiopathology

Chemical & Substance for Abstract: Hypothalamic-pituitary-adrenal axis dysregulation among diabetic outpatients. Information

Substance Name: Adrenocorticotropic Hormone

Registry Number: 9002-60-2

Grant and Affiliation Information for Hypothalamic-pituitary-adrenal axis dysregulation among diabetic outpatients.

AFFILIATION: National Eye Institute, Bethesda, MD.

Country: IRELAND

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MEDLINETA: Psychiatry Res

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