[Hypokalemia, hypovolemia and electrocardiographic changes due to furosemide abuse: Report of one case.]

[Hypokalemia, hypovolemia and electrocardiographic changes due to furosemide abuse: Report of one case.] Research Abstract Details 

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[Hypokalemia, hypovolemia and electrocardiographic changes due to furosemide abuse: Report of one case.] Abstract Text:

César Aravena,Ignacio Salas,Rodrigo Tagle,Aquiles Jara,Rodrigo Miranda,Paul McNab,José A Rodríguez,Gloria Valdés,Andrés Valdivieso, Aravena,Ignacio Salas,Rodrigo Tagle,Aquiles Jara,Rodrigo Miranda,Paul McNab, ,Gloria , Valdivieso,

Hypokalemia (serum K+ < 3.5 mEq/1) is a potentially serious adverse effect of diuretic ingestión. We report a 27 year-old woman admitted with muscle weakness, a serum potassium of 2.0 mEq/1, metabolic alkalosis and EKG abnormalities simulating cardiac ischemia, that reverted with potassium chloride administration. She admitted high dose furosemide self-medication for edema. Glomerular filtration rate, tubular sodium reabsortion, potassium secretion, the renin-aldosterone system, total body water distribution and capillary permeability, were studied sequentially until 90 days after her admission. There was hyperactivity of the renin-aldosterone axis, reduction in extracellular and intracellular volumes, normal capillary permeability and high sodium tubular reabsorption, probably explained by a "rebound" salt retention associated with her decreased extracellular volume.

[Hypokalemia, hypovolemia and electrocardiographic changes due to furosemide abuse: Report of one case.] Publishing Authors By Initials

C Aravena,I Salas,R Tagle,A Jara,R Miranda,P McNab,JA Rodríguez,G Valdés,A Valdivieso,C Aravena,I Salas,R Tagle,A Jara,R Miranda,P McNab,JA ,G ,A Valdivieso,

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[Hypokalemia, hypovolemia and electrocardiographic changes due to furosemide abuse: Report of one case.] Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Revista médica de Chile

VOLUME: 135

Page Numbers: 1456-62

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ISSN: 0034-9887

DAY: 16

MONTH: 01

YEAR: 2008

[Hypokalemia, hypovolemia and electrocardiographic changes due to furosemide abuse: Report of one case.] Information

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LANGUAGE: spa

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AFFILIATION: Nefrología, Escuela de Medicina, Pontificia Universidad Católica de Chile, Santiago, Chile.

Country: Chile

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MEDLINETA: Rev Med Chil

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