[Hypokalemia can accelerate the development of cerebrovascular and cardiovascular disease]

[Hypokalemia can accelerate the development of cerebrovascular and cardiovascular disease] Research Abstract Details 

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[Hypokalemia can accelerate the development of cerebrovascular and cardiovascular disease] Abstract Text:

BACKGROUND: Hypokalaemia is known to precipitate cardiac arrhythmias. Hypokalaemia can also give rise to adverse cardiovascular effects not related to arrhythmias. MATERIAL AND METHODS: This article presents an evaluation of the relevant literature describing adverse effects of hypokalaemia and beneficial effects of potassium supplementation on cerebrovascular and cardiovascular disease. RESULTS AND INTERPRETATION: Diuretics-induced hypokalaemia may offset the beneficial effects of blood pressure reduction on cardiovascular events. In several epidemiological studies high intake of potassium in the food was associated with reduced risk of developing a stroke. Fruit and vegetables contain potassium, and an inverse correlation between intake of these nutrients and stroke has been described. In spontaneously hypertensive rats, potassium supplementation in the diet markedly reduced the risk of death, brain haemorrhage and infarct. Potassium reduces oxidative stress and proliferation of smooth muscle cells, i.e. factors involved in the development of atherosclerosis, and may have an antithrombotic effect.

[Hypokalemia can accelerate the development of cerebrovascular and cardiovascular disease] Publishing Authors By Initials

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[Hypokalemia can accelerate the development of cerebrovascular and cardiovascular disease] Journal Published:

PUBLICATION TYPE: Review

Journal: Tidsskrift for den Norske lægeforening : tidsskrif

VOLUME: 122

Page Numbers: 499-501

Journal Abbreviation: Tidsskr. Nor. Laegeforen.

ISSN: 0029-2001

DAY: 20

MONTH: Feb

YEAR: 2002

[Hypokalemia can accelerate the development of cerebrovascular and cardiovascular disease] Information

Number of References: 41

LANGUAGE: nor

NlmUniqueID: 413423

[Hypokalemia can accelerate the development of cerebrovascular and cardiovascular disease] Keywords Mesh Terms:

KEYWORDS: Sodium Chloride Symporter Inhibitors

MESH TERMS: adverse effects

Chemical & Substance for Abstract: [Hypokalemia can accelerate the development of cerebrovascular and cardiovascular disease] Information

Substance Name: Potassium

Registry Number: 7440-09-7

Grant and Affiliation Information for [Hypokalemia can accelerate the development of cerebrovascular and cardiovascular disease]

AFFILIATION: Institutt for farmakoterapi Postboks 1065 Blindern 0316 Oslo. k.h.landmark@ioks.uio.no

Country: Norway

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MEDLINETA: Tidsskr Nor Laegeforen

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